Protein Alignment MFS10 and SLC37A2

DIOPT Version :10

• Sequence 1: NP_572857.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_938018.1
• Gene: SLC37A2 / 219855
• HGNCID: 20644
• Length: 505
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 113/541 - (20%)
• Similarity: 210/541 - (38%)
• Gaps: 116/541 - (21%)

  Fly    68 RHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIP-----HSNSSVIDTDTCPLPAPHHNGSDP 127
            |.:...:.||.:|..:..|..:|: :.:.::|....     :...|:.||..|.. ||.    |.
Human    22 RGLILLLTFLIYACYHMSRKPISI-VKSRLHQNCSEQIKPINDTHSLNDTMWCSW-APF----DK 80

  Fly   128 NPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAH 192
            :..||        ..|.|..:|...|.:.....|...|....:.....|:|::.:||.:..|...
Human    81 DNYKE--------LLGGVDNAFLIAYAIGMFISGVFGERLPLRYYLSAGMLLSGLFTSLFGLGYF 137

  Fly   193 WDLPLL---VLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAG-W 253
            |::..|   |::::..|:.:...:|::...:.:|....:|.....|..:.:::|.::...:|| |
Human   138 WNIHELWYFVVIQVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNILGSLIAGIW 202

  Fly   254 LCSLDFLGGWPSAFYIFGLL-GILWFIAWMYLVYDKPSD--------HPRISESEREYIERSLQV 309
            :     .|.|..:|.:.|:: .::..|.:::|: :.|.|        |...:|
Human   203 V-----NGQWGLSFIVPGIITAVMGVITFLFLI-EHPEDVDCAPPQHHGEPAE------------ 249

  Fly   310 QRLINQDLAEAEEEEGQDEVSLR------------APPEEP----------IPWSSLLTSVPLWA 352
                |||   ..|:.|....|:|            .|.|||          ||.....:...|:|
Human   250 ----NQD---NPEDPGNSPCSIRESGLETVAKCSKGPCEEPAAISFFGALRIPGVVEFSLCLLFA 307

  Fly   353 ILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSALADW------- 410
            .|::        ||.|..||.|::|:.||..:....|:.:..:.....||....::|:
Human   308 KLVS--------YTFLYWLPLYIANVAHFSAKEAGDLSTLFDVGGIIGGIVAGLVSDYTNGRATT 364

  Fly   411 -----MLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTFMLAGVGSFGGAVYAGNQ 470
                 :||...:.|.| |...:.:||.:..|.:.|.:..|...:..|.:.|.:|:     :...:
Human   365 CCVMLILAAPMMFLYN-YIGQDGIASSIVMLIICGGLVNGPYALITTAVSADLGT-----HKSLK 423

  Fly   471 MNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLVFWLAAGLNIAGNFIYL 535
            .|..|||     |:..|.:...:|...|.|.:.|||     :.|.|:.||::....::....:..
Human   424 GNAKALS-----TVTAIIDGTGSIGAALGPLLAGLI-----SPTGWNNVFYMLISADVLACLLLC 478

  Fly   536 IFASAEEQSWSKTPPTRNSRS 556
            .....|..:| |...:|.|.|
Human   479 RLVYKEILAW-KVSLSRGSGS 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_572857.1	MFS_SLC17	73..538	CDD:340876	106/516 (21%)
SLC37A2	NP_938018.1	MFS_SLC37A1_2	22..484	CDD:340902	107/524 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..262		7/40 (18%)