DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	501	Identity:	150/501 - (29%)
Similarity:	259/501 - (51%)	Gaps:	50/501 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 PKTRHIFGF----------MGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTD--TCPL 117
            |.||...||          |.|..|.:: ..||:||:||:||||.|  .|.:.:...|:  ...|
Mouse     5 PTTRKGSGFCSLRYALALIMHFSNFTMI-TQRVSLSIAIIAMVNST--QHQDPANASTEGPVMDL 66

  Fly   118 PAPHHNGSDPNPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAV 182
            .:....|......:...:.|...|||::..|..||.:||.:|.|.:|.::|.|:|.|.|:||:::
Mouse    67 LSNQSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSL 131

  Fly   183 FTLITPLAAHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVIS 247
            .||.|||||.:.:.|::::|.::||.:|:.:.....:.|.|.|||||:|..:|..:|.::|:|
Mouse   132 LTLFTPLAADFGVILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSV-- 194

  Fly   248 MPLAGW-----LCSLDFLGGWPSAFYIFGL-LGILWFIAWMYLVYDKPSDHPRISESEREYIERS 306
                 |     ||....|.|...|||:..| :|.:..:.|..::||.|..||.||..|:|:|..|
Mouse   195 -----WVLHHPLCGRINLTGTGLAFYLLHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEHITSS 254

  Fly   307 LQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTEL 371
            :..|                     .:.|...:|..:::..:|||||.:......|.....:|.|
Mouse   255 VAQQ---------------------SSSPRRSVPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYL 298

  Fly   372 PTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSL 436
            |||:|.:||.:|:.:.:|:::|::.:....|....:||::|:|..:||:...||::::..::|||
Mouse   299 PTYISTVLHVNIRDSGVLSSLPFIAASSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSL 363

  Fly   437 GLIGIIYVGCDWVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPY 501
            ..:.:.:|...::....:|..:........:|..:|.:.::||||..:.||:.......|.::..
Mouse   364 CAVALPFVTSSYIATIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISST 428

  Fly   502 VIGLIINHRETLTQWHLVFWLAAGLNIAGNFIYLIFASAEEQSWSK 547
            ..|.:|: :::.:.|..||:|:|.:|:.|...||||..||.|||:|
Mouse   429 TTGFLIS-QDSESGWRNVFFLSAAVNMFGLIFYLIFGQAEIQSWAK 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	149/499 (30%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	120/409 (29%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	138/474 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810