DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and Y51B9A.6

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_001254210.1	Gene:	Y51B9A.6 / 190139	WormBaseID:	WBGene00013088	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	549	Identity:	119/549 - (21%)
Similarity:	220/549 - (40%)	Gaps:	95/549 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SASAERSD-----DEADDEREAFCSGERPLIRSSGAAEENHGCGPKTRHIFGFMGFLGFAVVYAM 85
            |||:|.:.     |:.|.|                  |..:||....|:|...:|....:.:.:.
Worm     2 SASSETTSSGTICDQVDKE------------------EGRYGCRGANRYIILVIGLFFLSFLLSS 48

  Fly    86 RVNLSVAIVAMVNQTAIPH------SNSSVIDTDTCPLPAPHHNGSDPN-PQKEGEFVWDEATQG 143
            .:..:...|:|||..:.|:      ||.|:.:.          |.:||: |..:..|.:|...:.
Worm    49 IICYNACYVSMVNPQSSPYWEDFVNSNKSLDEI----------NWNDPDLPLSQRRFAFDTTQKS 103

  Fly   144 LVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWDLPLLVLVRILEGMG 208
            |...:.|.|.:...||..|:...:|..|:.....::.....:|||:...|..|:.|::|:|:|:.
Worm   104 LGFAAGFLGAIAAVVPMSRLTARFGVHKVMTLSGILGTFLVVITPIVITWSFPVFVILRVLQGIT 168

  Fly   209 EGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSAFYIFG-L 272
            ....:.....::..|....|:..|.:::.|...:|.|.:||::|.|.:   ..|||..||:.| :
Worm   169 LANLFTTAGVVVNEWAAVNEKGLFISVLSAHVEMGAVFTMPVSGALAT---SAGWPWVFYLHGAI 230

  Fly   273 LGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPPEE 337
            ||.| .|.|.....|:...||.:...|    .|.:...:.::|      ..:|.:|..:|
Worm   231 LGAL-TILWAVYYRDRAVKHPFVQRKE----WRKISFGKKLDQ------TGKGSNETPIR----- 279

  Fly   338 PIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSWFVGI 402
                 .:::|:.:|.:.:...|........::..|.|:..::........||..:|......:..
Worm   280 -----KIVSSIVIWGVWIAVIGNFLVSQFSISYAPIYLRGVIGCTPTEAGLLTLIPMACLLVIKF 339

  Fly   403 ACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGC---------DWVWVTFMLAGV 458
            :....:|.:   :.||.|...|::|:.|.:..|   |..|.:.|         |.:.::..:|.:
Worm   340 STGFFSDRI---KSISDLTKMKMFNSCALLGSS---IFFIILSCSSPGGSKVLDVILLSIPMALL 398

  Fly   459 G-SFGG----AVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHL 518
            | |.||    ||....|     .||.....:..|..|:.....||.|     .:...::.::|..
Worm   399 GFSSGGYSKCAVMVSGQ-----YSPFVMSIVQIIACSSLMAGSFLVP-----ALTPSDSFSEWQR 453

  Fly   519 VFWLAAGLNIAGNFIYLIFASAEEQSWSK 547
            ||.:...:....|.|:::||.||...|::
Worm   454 VFMIYGAVLAITNTIFIVFARAEPAKWAQ 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	110/505 (22%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	89/418 (21%)
Y51B9A.6	NP_001254210.1	MFS	50..473	CDD:391944	101/472 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920