Protein Alignment MFS10 and SLC17A3

DIOPT Version :9

• Sequence 1: NP_001285188.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 476
• Identity: 134/476 - (28%)
• Similarity: 241/476 - (50%)
• Gaps: 35/476 - (7%)

  Fly    76 FLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQ----KEGEFV 136
            |..|..: |..|.:::.:|||||.|    |..|.::..:..||.....|....|:    |...:.
Human    47 FCNFTTI-AQNVIMNITMVAMVNST----SPQSQLNDSSEVLPVDSFGGLSKAPKSLPAKAPVYD 106

  Fly   137 WDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWDLPLLVLV 201
            |....||::.|:..||.:||..|.|.:|...|.|::.|..:..|:..||..|||..:.:.||::.
Human   107 WSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLTLCIPLATDFGIVLLIVT 171

  Fly   202 RILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSA 266
            ||::|:.:........|:...|.||.||::..:|..:|..:|...::.:.|::..   ..|||..
Human   172 RIVQGLSQSSILGGQFAIWEKWGPPQERSRLCSIALSGMLLGCFTAILIGGFISE---TLGWPFV 233

  Fly   267 FYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSL 331
            |||||.:|.:..:.|..::||.|..:|.||.||:|||..||             :::.|..
Human   234 FYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIISSL-------------KQQVGSS---- 281

  Fly   332 RAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLT 396
                ::|:|..::|.|:|:|:|.|......|...|.:..:|||:|::.|.:|:.|.||:|:|::.
Human   282 ----KQPLPIKAMLRSLPIWSICLGCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGLLSALPFIV 342

  Fly   397 SWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTFMLAGVGSF 461
            :|.:|:....|||::|.::: .|:...|:...:.|:..|..::.:.|:...::..|.:|......
Human   343 AWVIGMVGGYLADFLLTKKF-RLITVRKIATILGSLPSSALIVSLPYLNSGYITATALLTLSCGL 406

  Fly   462 GGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLVFWLAAGL 526
            .....:|..:|.:.::|||:..:.|.:...::|...:.|.|.|.::: ::....|..||:|...:
Human   407 STLCQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLLS-QDPEFGWRNVFFLLFAV 470

  Fly   527 NIAGNFIYLIFASAEEQSWSK 547
            |:.|...||||..|:.|.|:|
Human   471 NLLGLLFYLIFGEADVQEWAK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	133/474 (28%)
		MFS	134..538	CDD:119392	112/403 (28%)
SLC17A3	NP_001091956.1	2A0114euk	23..497	CDD:129972	134/476 (28%)
		MFS	98..481	CDD:119392	112/408 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810