Protein Alignment MFS10 and SLC17A2

DIOPT Version :9

• Sequence 1: NP_001285188.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001273052.1
• Gene: SLC17A2 / 10246
• HGNCID: 10930
• Length: 478
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 151/490 - (30%)
• Similarity: 251/490 - (51%)
• Gaps: 58/490 - (11%)

  Fly    74 MGFLGFAVVYAMRVNLSVAIVAMVNQT----------------AIPHSNSSVIDTDTCPLPAPHH 122
            |.|..|.:: ..||:||:||:||||.|                |..:|:.|:.:.||
Human    24 MHFSNFTMI-TQRVSLSIAIIAMVNTTQQQGLSNASTEGPVADAFNNSSISIKEFDT-------- 79

  Fly   123 NGSDPNPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLIT 187
                    |...:.|...|||::..|..||.:||.:|.|.:|.::|.||:.|.|:||:::.||.|
Human    80 --------KASVYQWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKKMLGAGLLISSLLTLFT 136

  Fly   188 PLAAHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAG 252
            ||||.:.:.|:::||.::||.:|:.:.....:.|.|.|||||:|...|..:||..|:.|.:.:.|
Human   137 PLAADFGVILVIMVRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTTIAGSGSAFGSFIILCVGG 201

  Fly   253 WLCSLDFLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDL 317
            .:..   ...||..|||||..|.:..:.|..::||.|..||.||..|:|:|..||..|
Human   202 LISQ---ALSWPFIFYIFGSTGCVCCLLWFTVIYDDPMHHPCISVREKEHILSSLAQQ------- 256

  Fly   318 AEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFD 382
                          .:.|...:|..:::|.:|||||.|......|.....||.||||:|.:||.:
Human   257 --------------PSSPGRAVPIKAMVTCLPLWAIFLGFFSHFWLCTIILTYLPTYISTLLHVN 307

  Fly   383 IQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCD 447
            |:.:.:|:::|::.:....|....|||::|:|..:.|:...||::::..::||:..:.:.:|...
Human   308 IRDSGVLSSLPFIAAASCTILGGQLADFLLSRNLLRLITVRKLFSSLGLLLPSICAVALPFVASS 372

  Fly   448 WVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRET 512
            :|....:|..:........:|..:|.:.::||||..:.||:.....|.|.::....|.:|: ::.
Human   373 YVITIILLILIPGTSNLCDSGFIINTLDIAPRYASFLMGISRGFGLIAGIISSTATGFLIS-QDF 436

  Fly   513 LTQWHLVFWLAAGLNIAGNFIYLIFASAEEQSWSK 547
            .:.|..||:|:|.:|:.|...||.|..||.|.|:|
Human   437 ESGWRNVFFLSAAVNMFGLVFYLTFGQAELQDWAK 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	150/488 (31%)
		MFS	134..538	CDD:119392	125/403 (31%)
SLC17A2	NP_001273052.1	2A0114euk	1..477	CDD:129972	151/490 (31%)
		MFS	81..461	CDD:119392	125/404 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810