Protein Alignment CG15717 and ALDH5A1

DIOPT Version :10

• Sequence 1: NP_572856.1
• Gene: CG15717 / 32262
• FlyBaseID: FBgn0030451
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_733936.1
• Gene: ALDH5A1 / 7915
• HGNCID: 408
• Length: 548
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 54/242 - (22%)
• Similarity: 90/242 - (37%)
• Gaps: 60/242 - (24%)

  Fly    20 QLQPTAQETKLALIPSAPQWRSPQLMVVFEDGDLHSARHQLLQSLQNPFAEG----SVATLLLQE 80
            :|:|.|.    .|:|::.....|..:..:. |.|......||::  :.|..|    :.||..:|:
Human    23 RLRPRAG----GLVPASGPAPGPAQLRCYA-GRLAGLSAALLRT--DSFVGGRWLPAAATFPVQD 80

  Fly    81 SIADQFVGLVA----QDLRPLS----------QEVS-KHPS------YTSTLAKIEELKAKTVQG 124
            ..:...:|:||    ::.|...          :||| |..|      |...:...::| |:.:..
Human    81 PASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDL-ARIITA 144

  Fly   125 ES---LKAGESPVLVYDCVHSYLGNGATGVV--TVHTFRTAKEAGQLAKRDPLPYGQV-SLWN-- 181
            ||   ||.....:|.......:....|..|.  .:||  .||:...|..:.|:....| :.||
Human   145 ESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHT--PAKDRRALVLKQPIGVAAVITPWNFP 207

  Fly   182 -----EKL------GCAYELIPR--LPSDIVAINCFNP----DLDPI 211
                 .|:      ||...:.|.  .|...:|:...|.    ||||:
Human   208 SAMITRKVGAALAAGCTVVVKPAEDTPFSALALAEVNQGFLLDLDPL 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15717	NP_572856.1	DUF1487	38..250	CDD:254173	49/224 (22%)
ALDH5A1	NP_733936.1	SSADH	78..541	CDD:188167	40/180 (22%)