DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15717 and Aldh1a3

DIOPT Version :9

Sequence 1:	NP_001285186.1	Gene:	CG15717 / 32262	FlyBaseID:	FBgn0030451	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_444310.3	Gene:	Aldh1a3 / 56847	MGIID:	1861722	Length:	512	Species:	Mus musculus

Alignment Length:	202	Identity:	45/202 - (22%)
Similarity:	72/202 - (35%)	Gaps:	62/202 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VVFEDGDLHSA---RHQLLQSLQNPFAEGSVAT----LLLQESIADQFVGLVAQDLRPLSQEVSK 103
            :|..|.||..|   .||.:.     |.:|...|    :.::|.:..:||       |...:...|
Mouse   288 IVCADADLDLAVECAHQGVF-----FNQGQCCTAASRVFVEEQVYGEFV-------RRSVEFAKK 340

  Fly   104 HPSYTSTLAKIEELKAKTVQG------------ESLKAGESPVLVYDCVHSYLGNGATGV----- 151
            .|..       :...|||.||            |.:::|:......:|..|.:.:....:
Mouse   341 RPVG-------DPFDAKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDRGLFIKPTVF 398

  Fly   152 --VTVHTFRTAKE--------------AGQLAKR-DPLPYG-QVSLWNEKLGCAYELIPRLPSDI 198
              || ...|.|||              ..::.|| :...|| ..:::.:.|..|.:|...|.|..
Mouse   399 SDVT-DNMRIAKEEIFGPVQPILKFKNLEEVIKRANSTDYGLTAAVFTKNLDKALKLAAALESGT 462

  Fly   199 VAINCFN 205
            |.|||:|
Mouse   463 VWINCYN 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15717	NP_001285186.1	DUF1487	38..250	CDD:254173	45/202 (22%)
Aldh1a3	NP_444310.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
Aldh1a3	NP_444310.3	ALDH_F1AB_F2_RALDH1	26..506	CDD:143459	45/202 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900