DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15717 and CG8665

DIOPT Version :9

Sequence 1:	NP_001285186.1	Gene:	CG15717 / 32262	FlyBaseID:	FBgn0030451	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_610107.1	Gene:	CG8665 / 35407	FlyBaseID:	FBgn0032945	Length:	913	Species:	Drosophila melanogaster

Alignment Length:	194	Identity:	40/194 - (20%)
Similarity:	80/194 - (41%)	Gaps:	33/194 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RSPQLMVVFEDGDLHSARHQLLQSL-----QNPFAEGSVATLLLQESIADQFVGLVAQDLR---- 95
            :||  :::|.|.|:..|....:.|:     :|..|.|   .|.:::.|.|:|:..|.:|||
  Fly   687 KSP--LIIFADCDMDKAVKHGMSSVFFNKGENCIAAG---RLFVEDRIHDEFIRRVLKDLRTMTI 746

  Fly    96 --PLSQEVSKHP-SYTSTLAKIEELKAKTV-QGESLKAGE-----------SPVL---VYDCVHS 142
              ||.:..:..| ::.:...|:.|...:.| :|..|..|.           :|.:   |.|.:..
  Fly   747 GDPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPNLKGYFFTPTVFTNVTDDMFI 811

  Fly   143 YLGNGATGVVTVHTFRTAKEAGQLAKRDPLPYGQVS-LWNEKLGCAYELIPRLPSDIVAINCFN 205
            ........::.:..|..:.....:.:.:...||..| ::.:.:|.|.....|:.:..|.:|.:|
  Fly   812 AQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYN 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15717	NP_001285186.1	DUF1487	38..250	CDD:254173	40/194 (21%)
CG8665	NP_610107.1	Fmt	4..315	CDD:223301
		FMT_core	5..207	CDD:294280
		FDH_Hydrolase_C	212..316	CDD:187731
		PP-binding	338..403	CDD:278949
		PLN02466	396..909	CDD:215259	40/194 (21%)
		ALDH_F1L_FTFDH	428..913	CDD:143458	40/194 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900