Protein Alignment CG15717 and ALDH1A1

DIOPT Version :10

• Sequence 1: NP_572856.1
• Gene: CG15717 / 32262
• FlyBaseID: FBgn0030451
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_000680.2
• Gene: ALDH1A1 / 216
• HGNCID: 402
• Length: 501
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 45/205 - (21%)
• Similarity: 74/205 - (36%)
• Gaps: 60/205 - (29%)

  Fly    40 RSPQLMVVFEDGDLHS----ARHQLLQSLQNPFAEG----SVATLLLQESIADQFVGLVAQDLR- 95
            :||  .:|..|.||.:    |.|.:.      :.:|    :.:.:.::|||.|:||....:..:
Human   273 KSP--CIVLADADLDNAVEFAHHGVF------YHQGQCCIAASRIFVEESIYDEFVRRSVERAKK 329

  Fly    96 -----PLSQEVSKHP-----SYTSTLAKIEELKAKTVQGESLKAGESP-----VLVYDCVHSYLG 145
                 ||:..|::.|     .|...|..||..|.   :|..|:.|..|     ..|...|.|.:
Human   330 YILGNPLTPGVTQGPQIDKEQYDKILDLIESGKK---EGAKLECGGGPWGNKGYFVQPTVFSNV- 390

  Fly   146 NGATGVVTVHTFRTAKE-----AGQLAKRDPLP----------YG-QVSLWNEKLGCAYELIPRL 194
                    ....|.|||     ..|:.|...|.          || ...::.:.:..|..:...|
Human   391 --------TDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSAL 447

  Fly   195 PSDIVAINCF 204
            .:..|.:||:
Human   448 QAGTVWVNCY 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15717	NP_572856.1	DUF1487	38..250	CDD:254173	45/205 (22%)
ALDH1A1	NP_000680.2	ALDH_F1AB_F2_RALDH1	15..495	CDD:143459	45/205 (22%)
		Mediates interaction with PRMT3. /evidence=ECO:0000269|PubMed:33495566	336..501		29/134 (22%)