Protein Alignment CG15717 and ALDH1L2

DIOPT Version :10

• Sequence 1: NP_572856.1
• Gene: CG15717 / 32262
• FlyBaseID: FBgn0030451
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_001029345.2
• Gene: ALDH1L2 / 160428
• HGNCID: 26777
• Length: 923
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 48/230 - (20%)
• Similarity: 90/230 - (39%)
• Gaps: 42/230 - (18%)

  Fly     5 FTQSQPSRITSYMVNQLQPTAQETKLALIPSAPQWRSPQLMVVFEDGDLHSARHQLLQSL----- 64
            ||.|.|      :..|:..:...:.|..:......:||  :::|.|.:|..|....:.::
Human   669 FTGSTP------IGKQIMKSCAVSNLKKVSLELGGKSP--LIIFNDCELDKAVRMGMGAVFFNKG 725

  Fly    65 QNPFAEGSVATLLLQESIADQFVGLVAQDLR------PLSQEV----SKHPSYTSTLAKIEELKA 119
            :|..|.|   .|.::|||.|:||..|.::::      ||.:..    ..|.::...|.:..|...
Human   726 ENCIAAG---RLFVEESIHDEFVTRVVEEIKKMKIGDPLDRSTDHGPQNHKAHLEKLLQYCETGV 787

  Fly   120 KTVQGESLKAGESPV---------LVYDCVHSYL----GNGATGVVTVHTFRTAKEAGQLAKRDP 171
            |  :|.:|..|...|         .|:..|..|:    ......::.:..|:.....|.|.:.:.
Human   788 K--EGATLVYGGRQVQRPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANS 850

  Fly   172 LPYGQVS-LWNEKLGCAYELIPRLPSDIVAINCFN 205
            ..||..| ::...:..|..:..:|.:..|.||.:|
Human   851 TEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYN 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15717	NP_572856.1	DUF1487	38..250	CDD:254173	42/197 (21%)
ALDH1L2	NP_001029345.2	Hydrolase domain. /evidence=ECO:0000250|UniProtKB:P28037	23..331
		FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..>390	CDD:425746
		Aldehyde dehydrogenase domain. /evidence=ECO:0000250|UniProtKB:P28037	438..923		48/230 (21%)
		ALDH_F1L_FTFDH	439..923	CDD:143458	48/230 (21%)