DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15717 and Aldh1l1

DIOPT Version :9

Sequence 1:	NP_001285186.1	Gene:	CG15717 / 32262	FlyBaseID:	FBgn0030451	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001343341.1	Gene:	Aldh1l1 / 107747	MGIID:	1340024	Length:	902	Species:	Mus musculus

Alignment Length:	193	Identity:	43/193 - (22%)
Similarity:	86/193 - (44%)	Gaps:	32/193 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RSPQLMVVFEDGDLHSARHQLLQSL-----QNPFAEGSVATLLLQESIADQFVGLVAQDL----- 94
            :||  :::|.|.||:.|....:.|:     :|..|.|   .|.:::||.||||..|.:::
Mouse   677 KSP--LIIFADCDLNKAVQMGMSSVFFNKGENCIAAG---RLFVEDSIHDQFVQKVVEEVGKMKI 736

  Fly    95 -RPLSQEVSKHP-SYTSTLAKIEELKAKTV-QGESLKAGESPV---------LVYDCV--HSYLG 145
             .||.::.:..| ::.:.|.|:.|...:.| :|.:|..|.:.|         .|:..|  |.|:.
Mouse   737 GNPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIA 801

  Fly   146 NGAT--GVVTVHTFRTAKEAGQLAKRDPLPYGQVS-LWNEKLGCAYELIPRLPSDIVAINCFN 205
            ...:  .::.:..|........|::.:...:|..| ::...:..|..:..:|.:..|.:|.:|
Mouse   802 KEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTRDINKALYVSDKLQAGTVFVNTYN 864

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15717	NP_001285186.1	DUF1487	38..250	CDD:254173	43/193 (22%)
Aldh1l1	NP_001343341.1	FMT_core_FDH_N	1..203	CDD:187716
		GART	1..203
		Substrate binding. /evidence=ECO:0000250	88..90
		FDH_Hydrolase_C	206..306	CDD:187731
		PP-binding	325..391	CDD:306928
		ALDH_F1L_FTFDH	417..902	CDD:143458	43/193 (22%)
		Aldehyde dehydrogenase	417..902		43/193 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900