DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15717 and aldh1l2

DIOPT Version :9

Sequence 1:	NP_001285186.1	Gene:	CG15717 / 32262	FlyBaseID:	FBgn0030451	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_002661418.2	Gene:	aldh1l2 / 100333269	ZFINID:	ZDB-GENE-100426-6	Length:	923	Species:	Danio rerio

Alignment Length:	227	Identity:	47/227 - (20%)
Similarity:	92/227 - (40%)	Gaps:	36/227 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FTQSQPSRITSYMVNQLQPTAQETKLALIPSAPQWRSPQLMVVFEDGDLHSARHQLLQSLQNPFA 69
            ||.|.|      :..|:..:...:.|..:......:||  :::|.|.|:..|....:.|:.....
Zfish   669 FTGSTP------IGKQIMKSCAVSNLKKVSLELGGKSP--LIIFSDCDMDKAVRMGMSSVYFNKG 725

  Fly    70 EGSVAT--LLLQESIADQFVGLVAQDLR------PLSQEV----SKHPSYTSTLAKIEELKAKTV 122
            |..:|.  |.::|||.|:::..|.::::      ||.:..    ..|.::...|.:..|:..|
Zfish   726 ENCIAAGRLFVEESIHDEYIRRVVEEIKKMKIGDPLDRSTDHGPQNHKAHMDKLVEYCEIGVK-- 788

  Fly   123 QGESLKAG----------ESPVLVYDCV-HSYLGNGAT--GVVTVHTFRTAKEAGQLAKRDPLPY 174
            :|.:|..|          ..|.:..|.. |.::....:  .|:.|..|:.....|.|::.:...:
Zfish   789 EGATLVYGGRQVDRPGFFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFKDGDVDGVLSRANDTEF 853

  Fly   175 GQVS-LWNEKLGCAYELIPRLPSDIVAINCFN 205
            |..| ::...:..|..:..||.:..|.||.:|
Zfish   854 GLASGVFTRDINKAMYVSERLEAGTVFINTYN 885

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15717	NP_001285186.1	DUF1487	38..250	CDD:254173	41/194 (21%)
aldh1l2	XP_002661418.2	Fmt	22..323	CDD:223301
		FMT_core_FDH_N	23..225	CDD:187716
		FDH_Hydrolase_C	228..327	CDD:187731
		PP-binding	346..412	CDD:278949
		ALDH_F1L_FTFDH	438..923	CDD:143458	47/227 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900