DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42237 and Pla2g3

DIOPT Version :9

Sequence 1:	NP_572855.1	Gene:	CG42237 / 32261	FlyBaseID:	FBgn0250862	Length:	363	Species:	Drosophila melanogaster
Sequence 2:	NP_001099485.1	Gene:	Pla2g3 / 289733	RGDID:	1305323	Length:	506	Species:	Rattus norvegicus

Alignment Length:	200	Identity:	59/200 - (29%)
Similarity:	87/200 - (43%)	Gaps:	24/200 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 DKEGKMLLEGL--SHYNRPLEIKFDE---MLKLMDQCEHVDKLSYASRH-------------KSK 211
            |.:|..|.:.|  :|:...:.|:.||   :......|.| :.|.:|..|             :|:
  Rat    51 DAQGLALFQALWDAHHRLQVCIRQDESELIAAFRALCAH-EPLRHAFIHTPGPELQRALATLQSQ 114

  Fly   212 LEGGERSNGGSASATTGGANDGVALKLATNIFPRSPFSLLSGIIPGTKWCGTGDIAETYSDLGSE 276
            .|...||......|......:........:...|..::     ||||.|||.|:.||..|:||..
  Rat   115 WEACRRSEASPTGAREKRETEHRGAPAGEHQRRRRGWT-----IPGTLWCGVGNSAENASELGMF 174

  Fly   277 MAMDRCCRQHDLCPIKIRAYQNKYELMNDSLYTKSHCICDDMLFSCLKMTNTSASQLMGSIYFNL 341
            ...|.|||:||.||..|...|..|.:.|...:|.|||.||.....||:....|.:.:||..:||:
  Rat   175 HGPDFCCREHDQCPQTISPLQYNYGIRNFRFHTISHCDCDARFQQCLRSQGDSIADIMGVAFFNV 239

  Fly   342 VQVPC 346
            :::||
  Rat   240 LEIPC 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42237	NP_572855.1	PLA2_bee_venom_like	254..348	CDD:153093	39/92 (42%)
Pla2g3	NP_001099485.1	PLA2_bee_venom_like	151..247	CDD:153093	39/98 (40%)
Pla2g3	NP_001099485.1	PLA2_group_III_like	299..424	CDD:153094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12253
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.970