DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3HCH and FTMT

DIOPT Version :9

Sequence 1:	NP_572854.1	Gene:	Fer3HCH / 32260	FlyBaseID:	FBgn0030449	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_803431.1	Gene:	FTMT / 94033	HGNCID:	17345	Length:	242	Species:	Homo sapiens

Alignment Length:	166	Identity:	75/166 - (45%)
Similarity:	103/166 - (62%)	Gaps:	4/166 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMTY 80
            |||||....|..:|.|||:||.||:.||:|||:|.|.|::.....|:||..|.||.|||||:|..
Human    68 VRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRL 132

  Fly    81 MNKRGGLIILSSVPQP-LPCFASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIEANF 144
            .|:|||.|.|..:.:| ...:.|.|.|::.|:.:|..||:.||:|||||..:.||:||||:|..:
Human   133 QNQRGGRIRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYY 197

  Fly   145 LQEQVDGQKILADYISQLEK---AQNQVGEFLFDKY 177
            |.|||...|.|.|::..|.|   ....:.|:|||.:
Human   198 LNEQVKSIKELGDHVHNLVKMGAPDAGLAEYLFDTH 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3HCH	NP_572854.1	Euk_Ferritin	24..177	CDD:153114	70/156 (45%)
Fer3HCH	NP_572854.1	Ferritin	25..165	CDD:278632	66/143 (46%)
FTMT	NP_803431.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	47..71		2/2 (100%)
		Euk_Ferritin	73..233	CDD:153114	70/159 (44%)
		Ferritin	77..218	CDD:278632	65/140 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142877
Domainoid	1	1.000	128	1.000	Domainoid score	I5305
eggNOG	1	0.900	-	-		E1_COG1528
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110661
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4447
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249457at2759
OrthoFinder	1	1.000	-	-		FOG0000169
OrthoInspector	1	1.000	-	-		otm41906
orthoMCL	1	0.900	-	-		OOG6_100688
Panther	1	1.100	-	-	O	PTHR11431
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4342
SonicParanoid	1	1.000	-	-		X152
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.830