DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3HCH and Ftmt

DIOPT Version :9

Sequence 1:	NP_572854.1	Gene:	Fer3HCH / 32260	FlyBaseID:	FBgn0030449	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_080562.2	Gene:	Ftmt / 67634	MGIID:	1914884	Length:	237	Species:	Mus musculus

Alignment Length:	173	Identity:	77/173 - (44%)
Similarity:	109/173 - (63%)	Gaps:	11/173 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMTY 80
            |||||....|..:|.|||:||.||:.||:|||:|.|.|::.....::||:.|:||||||||:|..
Mouse    64 VRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALYNFSKYFLRQSLEEREHAEKLMKL 128

  Fly    81 MNKRGGLIILSSVPQP----LPCFASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIE 141
            .|:|||.|.|..:.:|    ..|   .|.|::.|:.:|..||:.|||||.||.::.||:||||:|
Mouse   129 QNQRGGRICLQDIKKPDKDDWEC---GLRAMECALLLEKNVNQSLLDLHTLASEKGDPHLCDFLE 190

  Fly   142 ANFLQEQVDGQKILADYISQL---EKAQNQVGEFLFDKY-MGS 180
            .::|.|||...|.|.|::..|   ......:.|:||||: :||
Mouse   191 THYLHEQVKSIKELGDHVHNLVTMGAPAAGLAEYLFDKHTLGS 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3HCH	NP_572854.1	Euk_Ferritin	24..177	CDD:153114	69/159 (43%)
Fer3HCH	NP_572854.1	Ferritin	25..165	CDD:278632	65/146 (45%)
Ftmt	NP_080562.2	Euk_Ferritin	69..229	CDD:153114	69/162 (43%)
Ftmt	NP_080562.2	Ferritin	73..211	CDD:278632	64/140 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833001
Domainoid	1	1.000	126	1.000	Domainoid score	I5380
eggNOG	1	0.900	-	-		E1_COG1528
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H110661
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4494
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249457at2759
OrthoFinder	1	1.000	-	-		FOG0000169
OrthoInspector	1	1.000	-	-		otm43954
orthoMCL	1	0.900	-	-		OOG6_100688
Panther	1	1.100	-	-	O	PTHR11431
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4342
SonicParanoid	1	1.000	-	-		X152
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.830