DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3HCH and Ripor2

DIOPT Version :9

Sequence 1:	NP_572854.1	Gene:	Fer3HCH / 32260	FlyBaseID:	FBgn0030449	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_001014031.2	Gene:	Ripor2 / 306934	RGDID:	1306939	Length:	1310	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	53/177 - (29%)
Similarity:	93/177 - (52%)	Gaps:	35/177 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MCMLVRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEK 76
            |...:|||::...|..:|..:|:.|:||:.||::.:.||..|::..|
  Rat  1151 MTSQIRQNYSTEVEAAVNRLVNLHLRASYTYLSLGFFFDPDDVALEG------------------ 1197

  Fly    77 IMTYMNKRGGLIILSSVPQPLPC-FASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFI 140
                 |:|||..:...|.:|... :..||:|::.|:.:|..:|:.|||||||.....||:||||:
  Rat  1198 -----NERGGRALFQDVQKPSQDEWGKTLEAMEAALALEKNLNQALLDLHALGSARTDPHLCDFL 1257

  Fly   141 EANFLQEQVDGQKILADYISQLEK-----------AQNQVGEFLFDK 176
            |::||.::|...|.:.::::.|.:           ||..:||:||::
  Rat  1258 ESHFLDKEVKLIKKMGNHLTNLRRVAGPQPAQTGVAQASLGEYLFER 1304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3HCH	NP_572854.1	Euk_Ferritin	24..177	CDD:153114	49/165 (30%)
Fer3HCH	NP_572854.1	Ferritin	25..165	CDD:278632	43/151 (28%)
Ripor2	NP_001014031.2	PL48	118..529	CDD:292525
		Involved in cell filopodia formation. /evidence=ECO:0000250\|UniProtKB:Q9Y4F9	196..254
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	588..639
		PI-PLCc_GDPD_SF	<963..>1097	CDD:301322
		Ferritin_like	1160..1304	CDD:294190	49/166 (30%)
		Ferritin	1164..1282	CDD:278632	43/140 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46042
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810