DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Fer3HCH and ftn-2

DIOPT Version :9

Sequence 1:	NP_572854.1	Gene:	Fer3HCH / 32260	FlyBaseID:	FBgn0030449	Length:	186	Species:	Drosophila melanogaster
Sequence 2:	NP_491198.1	Gene:	ftn-2 / 171934	WormBaseID:	WBGene00001501	Length:	170	Species:	Caenorhabditis elegans

Alignment Length:	163	Identity:	66/163 - (40%)
Similarity:	100/163 - (61%)	Gaps:	1/163 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LVRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMT 79
            |.|||:....|..:|.|||:||.||:.||:|:::|||.|::.|.:.:||.:.|.||||||.::|.
Worm     3 LARQNYHSEVEAAVNKQINIELYASYVYLSMSFYFDRDDVALPNIAKFFKEQSDEEREHATELMR 67

  Fly    80 YMNKRGGLIILSSVPQP-LPCFASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIEAN 143
            ..|.|||.::|..:.:| ...:.:.|.|.:.|:.:|...|:.||.||:.||...|.:|.||||..
Worm    68 VQNLRGGRVVLQDIQKPENDEWGTALKAFEAALALEKFNNESLLKLHSTAGNHNDAHLTDFIEEK 132

  Fly   144 FLQEQVDGQKILADYISQLEKAQNQVGEFLFDK 176
            :|.|||......|..::.|::....|||::|||
Worm   133 YLDEQVKSINEFARMVANLKRVGPGVGEYVFDK 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3HCH	NP_572854.1	Euk_Ferritin	24..177	CDD:153114	62/154 (40%)
Fer3HCH	NP_572854.1	Ferritin	25..165	CDD:278632	56/140 (40%)
ftn-2	NP_491198.1	Euk_Ferritin	9..166	CDD:153114	62/157 (39%)
ftn-2	NP_491198.1	Ferritin	13..154	CDD:278632	56/140 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157380
Domainoid	1	1.000	105	1.000	Domainoid score	I4165
eggNOG	1	0.900	-	-		E1_COG1528
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I3276
Isobase	1	0.950	-	0	Normalized mean entropy	S2879
OMA	1	1.010	-	-		QHG48328
OrthoDB	1	1.010	-	-		D1249457at2759
OrthoFinder	1	1.000	-	-		FOG0000169
OrthoInspector	1	1.000	-	-		otm14386
orthoMCL	1	0.900	-	-		OOG6_100688
Panther	1	1.100	-	-	LDO	PTHR11431
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4342
SonicParanoid	1	1.000	-	-		X152
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750