Protein Alignment HOXC10 and ftz

DIOPT Version :10

• Sequence 1: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Sequence 2: NP_477498.1
• Gene: ftz / 40834
• FlyBaseID: FBgn0001077
• Length: 410
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 82/294 - (27%)
• Similarity: 115/294 - (39%)
• Gaps: 85/294 - (28%)

Human    51 PSLSKR---DEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCC 112
            |..:||   |:.:|...|:...||.|..|               :..|:....|.|..
  Fly    84 PKATKRKAEDDAASIIAAVEERPSTLRAL---------------LTNPVKKLKYTPDY------- 126

Human   113 MYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVPSY---YRASPSYSALDKTPHCSGANDFEAPF 174
            .|:..::.|..|..   |..:..|       |.|||   |...|:.||.:...:.    |..:|.
  Fly   127 FYTTVEQVKKAPAV---STKVTAS-------PAPSYDQEYVTVPTPSASEDVDYL----DVYSPQ 177

Human   175 EQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTP---SPNEIKTEQSLAGPKGSPSESEKERAK 236
            .|...|.                     ..|..||   :|..:...:.::.|..||.|.
  Fly   178 SQTQKLK---------------------NGDFATPPPTTPTSLPPLEGISTPPQSPGEK------ 215

Human   237 AADSSPDTSDNEAKEEIKAENTTG--NW--------LTAKSGRKKRCPYTKHQTLELEKEFLFNM 291
               ||...|.......:.|.|..|  ||        ...|..::.|..||::|||||||||.||.
  Fly   216 ---SSSAVSQEINHRIVTAPNGAGDFNWSHIEETLASDCKDSKRTRQTYTRYQTLELEKEFHFNR 277

Human   292 YLTRERRLEISKTINLTDRQVKIWFQNRRMKLKK 325
            |:||.||::|:..::|::||:||||||||||.||
  Fly   278 YITRRRRIDIANALSLSERQIKIWFQNRRMKSKK 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		17/96 (18%)
		Homeodomain	269..325	CDD:459649	33/55 (60%)
ftz	NP_477498.1	FTZ	1..248	CDD:397787	46/229 (20%)
		Homeodomain	255..311	CDD:459649	33/55 (60%)
		KLF1_2_4_N	<321..404	CDD:425360