Protein Alignment HOXC10 and bsh

DIOPT Version :10

• Sequence 1: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Sequence 2: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 79/342 - (23%)
• Similarity: 118/342 - (34%)
• Gaps: 88/342 - (25%)

Human    51 PSLSKRDEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLEQPVGRPLSSCSYPPSVKEENVCCMYS 115
            |:.||....:|.:..|.|              |..:.:|..:.:.|:|.|...:..:.|.....:
  Fly    23 PTHSKAAAMASATTMLTT--------------KTPFSIEHILFQNLNSASNNNNSSDTNGIAANT 73

Human   116 ---AEKRAKSGPEAAL---------YSHPLPESCLGEHEVPVPSYYRASPSYSALDKTPHCSGAN 168
               |.|.:::..::|.         :.||      .:|..|..|:..||.|.||.........|:
  Fly    74 NNYAPKSSRNAVKSARSAFAHDNNPHKHP------SQHSHPPQSHPPASASASATATARSNQAAS 132

Human   169 DFEA-PFEQRASLNPRAEHLE------------SPQLG-GKVSFPETPKSDSQTPSPNEIKTEQS 219
            .:.. .:.:.....||:.|..            |.||| |....|..|.:..|.|.|      ..
  Fly   133 GYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQHPPVPTTQPQPPPP------PP 191

Human   220 LAGPKG-------------------------SPSESEKE--------RAKAADSSPDTSDNEAKE 251
            |.|..|                         |||....:        :|.....:|.........
  Fly   192 LNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGAPFFGAPGCVP 256

Human   252 EIKAENTTG-NWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIW 315
            |:......| |.|.....||.|..::..|...|||.|....||:...|:|::..:.|::.|||.|
  Fly   257 ELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTW 321

Human   316 FQNRRMKLKKM--NREN 330
            |||||||.||.  .|:|
  Fly   322 FQNRRMKHKKQLRRRDN 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		23/130 (18%)
		Homeodomain	269..325	CDD:459649	24/55 (44%)
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	24/55 (44%)