Protein Alignment lic and STE7

DIOPT Version :10

• Sequence 1: NP_477162.1
• Gene: lic / 32257
• FlyBaseID: FBgn0261524
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_010122.1
• Gene: STE7 / 851396
• SGDID: S000002318
• Length: 515
• Species: Saccharomyces cerevisiae
• Alignment Length: 335
• Identity: 112/335 - (33%)
• Similarity: 167/335 - (49%)
• Gaps: 44/335 - (13%)

  Fly    11 TIAKEPEAAIVPPRNLDSRATIQIGDRTFDIDADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVK 75
            :|:..|....:.|...|.:.|:........|....|.::..:|.|..|.|.|..|.....::|.|
Yeast   156 SISLPPLEESLSPAAADLKDTLSGTSNGNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKK 220

  Fly    76 RIPMTVNIREQ------HRLVMDLDISMRSSDCPYTVHFYGAMYRE---GDVWICMEVMST-SLD 130
            .||:     ||      ::||.:|.|..........:.||||.|.:   .::.|.||.... |||
Yeast   221 TIPV-----EQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLD 280

  Fly   131 KFY--------------PKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKVIHRDVKPSNILIN 181
            |..              .|.:.::|     .:.|||..|::.|.:|:.|.|:||||:||||:|||
Yeast   281 KILSVYKRFVQRGTVSSKKTWFNEL-----TISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLIN 340

  Fly   182 RAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDVWSLGIGMIEMATG 246
            ..||:|:||||:|..|::|||.|. .|...||:||||  |||  .|.|:.||||||:.:||:.||
Yeast   341 SKGQIKLCDFGVSKKLINSIADTF-VGTSTYMSPERI--QGN--VYSIKGDVWSLGLMIIELVTG 400

  Fly   247 RYPYDNWR-TP---FEQLRQVVEDSPPRLP-EGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSF 306
            .:|..... ||   .:.|:::|.:..|||| :..:|.|..||:..|..|....|.:..:||.|..
Yeast   401 EFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDL 465

  Fly   307 IVEHLQRNTD 316
            |::::..:.|
Yeast   466 IMKYVSPSKD 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	106/302 (35%)
STE7	NP_010122.1	PKc_Byr1_like	185..482	CDD:270792	107/306 (35%)