Protein Alignment lic and MAP2K2

DIOPT Version :9

• Sequence 1: NP_477162.1
• Gene: lic / 32257
• FlyBaseID: FBgn0261524
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: XP_016882478.1
• Gene: MAP2K2 / 5605
• HGNCID: 6842
• Length: 512
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 107/325 - (32%)
• Similarity: 175/325 - (53%)
• Gaps: 70/325 - (21%)

  Fly    40 DIDADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPY 104
            ::..|..|:|.:||.|..|:|.|::|:.:..::|.|.|.:.:....:::::.:|.: :...:.||
Human    66 ELKDDDFERISELGAGNGGVVTKVQHRPSGLIMARKLIHLEIKPAIRNQIIRELQV-LHECNSPY 129

  Fly   105 TVHFYGAMYREGDVWICMEVM-STSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKV 168
            .|.||||.|.:|::.||||.| ..|||    :|.....|:.|.:|||::::|:..|.||..:.::
Human   130 IVGFYGAFYSDGEISICMEHMDGGSLD----QVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQI 190

  Fly   169 IHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDV 233
            :||||||||||:|..|::|:||||:||.|:||:|.:. .|.:.||||||:  ||  ..|.::||:
Human   191 MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSF-VGTRSYMAPERL--QG--THYSVQSDI 250

  Fly   234 WSLGIGMIEMATGRYPY----------------------------DNWRTP-------------- 256
            ||:|:.::|:|.||||.                            ...|.|
Human   251 WSMGLSLVELAVGRYPIPPPDAKELEAIFGRPVVDGEEGEPHSISPRPRPPGRPVSGHGMDSRPA 315

  Fly   257 ---FEQLRQVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSFIV-----EHLQR 313
               ||.|..:|.:.||:||.|.|:|:|::|:    .|.:     :|....||.::     :||.|
Human   316 MAIFELLDYIVNEPPPKLPNGVFTPDFQEFV----NKWF-----WEGRQPHSILLPPSTQQHLWR 371

  Fly   314  313
            Human   372  371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	107/321 (33%)
MAP2K2	XP_016882478.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2221
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.950