Protein Alignment lic and map2k1

DIOPT Version :10

• Sequence 1: NP_477162.1
• Gene: lic / 32257
• FlyBaseID: FBgn0261524
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_998584.2
• Gene: map2k1 / 406728
• ZFINID: ZDB-GENE-040426-2759
• Length: 395
• Species: Danio rerio
• Alignment Length: 400
• Identity: 122/400 - (30%)
• Similarity: 198/400 - (49%)
• Gaps: 80/400 - (20%)

  Fly     1 MSKRHRLTPFTIAKEPEAAIV-----PPRNLDS------------------RATIQIGDRTFDID 42
            |.||.:..|..:...|:...:     ...||::                  .|.:....:..::.
Zfish     1 MQKRRKPEPIQLNPIPDGNAINGTGATETNLEALQKKLEELELDEQQKKRLEAFLTQKQKVGELK 65

  Fly    43 ADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPYTVH 107
            .|..|||.:||.|..|:|.|:.|:.:..::|.|.|.:.:....:::::.:|.: :...:.||.|.
Zfish    66 DDDFEKISELGAGNGGVVFKVLHRPSGFIMARKLIHLEIKPAIRNQIIRELQV-LHECNSPYIVG 129

  Fly   108 FYGAMYREGDVWICMEVM-STSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKVIHR 171
            ||||.|.:|::.||||.| ..|||:...|..    ::.|.:|||::::|:..|.||..:.|::||
Zfish   130 FYGAFYSDGEISICMENMDGGSLDQCLKKAG----KIPEQILGKVSIAVIKGLSYLREKHKIMHR 190

  Fly   172 DVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDVWSL 236
            ||||||||:|..|::|:||||:||.|:||:|.:. .|.:.||:|||:  ||  ..|.::.|:||:
Zfish   191 DVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSF-VGTRSYMSPERL--QG--THYSVQPDIWSM 250

  Fly   237 GIGMIEMATGRYPY----------------------------------------DNWRTP---FE 258
            |:.::|||.||:|.                                        .:.|.|   ||
Zfish   251 GLSLVEMAIGRFPIPPPDAKELEQIFGQPLEGDPSASDTSPKPRPPGRPGSSYGPDSRPPMAIFE 315

  Fly   259 QLRQVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSFIVEHLQRNTDISEFVAR 323
            .|..:|.:.||:|| ..|..||:||:..||.|....|.:.:||:.||||.:......|.:.::..
Zfish   316 LLDYIVNEPPPKLP-SIFGAEFQDFVNKCLIKNPAERADLKQLMVHSFIKDSEAEEVDFAGWLCS 379

  Fly   324 ILDLPDAQPA 333
            .:.|  .|||
Zfish   380 TIGL--NQPA 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	110/325 (34%)
map2k1	NP_998584.2	PKc_MEK1	63..382	CDD:270816	110/329 (33%)