DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lic and Slik

DIOPT Version :9

Sequence 1:	NP_477162.1	Gene:	lic / 32257	FlyBaseID:	FBgn0261524	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_726441.1	Gene:	Slik / 37893	FlyBaseID:	FBgn0035001	Length:	1703	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	92/314 - (29%)
Similarity:	151/314 - (48%)	Gaps:	37/314 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 DID-ADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRL---VMDLDISMRSS 100
            |.| |:..|.:.:||.||:|.|.|.:||:.....|.|    ...:.::..|   ::::|| :...
  Fly    30 DTDPAEFWEMVGELGDGAFGKVYKAQHKEQKRFAAAK----MCQLEDEENLSDHMVEIDI-LSEI 89

  Fly   101 DCPYTVHFYGAMYREGDVWICMEVM-STSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHA 164
            ..|..|..|.|...:..:|:.:|.. ..:||....::   :..:.|..:..:...:...|.:||.
  Fly    90 KHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVEL---EKPLTEPQIAYVCKHMTEGLTFLHR 151

  Fly   165 QLKVIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPY-MAPERI---DPQGNPA 225
            . ||||||:|..|:|:...|.||:.|||:|.....::.|.......|| ||||.:   ..:.||
  Fly   152 N-KVIHRDLKAGNVLLTMEGGVKLADFGVSAKNKHTMQKHDTFIGTPYWMAPELVLCETFRDNP- 214

  Fly   226 QYDIRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLRQVVEDSPPRLPE-GTFSPEFEDFIAVCLQ 289
             ||.:.|:|||||.:||:|. ..|.::..:|...|.::.:..||:|.: ..:|.||.||:...|.
  Fly   215 -YDHKVDIWSLGITLIELAQ-MEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFNDFLKKSLV 277

  Fly   290 KEYMARPNYEQLLKHSFIVEHLQRNTDI-----------SEFVARILDLPDAQP 332
            |:...||..:.|::|:||    .||.|.           :|.|..::|....:|
  Fly   278 KDPQVRPTTDVLMQHAFI----NRNLDAKPIKDLLLEYKAEVVEEVVDDETEEP 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	87/301 (29%)
Slik	NP_726441.1	STKc_SLK_like	31..310	CDD:132942	87/294 (30%)
		S_TKc	37..295	CDD:214567	80/269 (30%)
		PKK	958..1095	CDD:289257
		PKK	1126..1266	CDD:289257
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910