Protein Alignment lic and Map3k3

DIOPT Version :10

• Sequence 1: NP_477162.1
• Gene: lic / 32257
• FlyBaseID: FBgn0261524
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_036077.1
• Gene: Map3k3 / 26406
• MGIID: 1346874
• Length: 626
• Species: Mus musculus
• Alignment Length: 344
• Identity: 90/344 - (26%)
• Similarity: 148/344 - (43%)
• Gaps: 61/344 - (17%)

  Fly     3 KRHRLTPFTIAK-------------------EPEAAIVPPRNLDSRATIQIGDRTFDIDADSLE- 47
            :||:...||:..                   :|...:   |:.||...:.:.:|.....:.|..
Mouse   299 RRHQGNLFTLVPSSRSLSTNGENMGVAVQYLDPRGRL---RSADSENALTVQERNVPTKSPSAPI 360

  Fly    48 -----KICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDIS---MRSSDCPY 104
                 |:  ||:||:|.|.......|...||.|::....:..|..:.|..|:..   :::.....
Mouse   361 NWRRGKL--LGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHER 423

  Fly   105 TVHFYGAMYREGD--VWICMEVMSTSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLK 167
            .|.:||.:....:  :.|.||.|.....|...|.:   ..:.|||..|....::..:.|||:.:
Mouse   424 IVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAY---GALTESVTRKYTRQILEGMSYLHSNM- 484

  Fly   168 VIHRDVKPSNILINRAGQVKICDFG---------ISGYLVDSIAKTIDAGCKPY-MAPERIDPQG 222
            ::|||:|.:|||.:.||.||:.|||         :||..:.|:..|      || |:||.|..:|
Mouse   485 IVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGIRSVTGT------PYWMSPEVISGEG 543

  Fly   223 NPAQYDIRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLRQVVEDSPPRLPEGTFSPEFEDFIAVC 287
                |..::||||||..::||.|.:.|:..:.......:...:.:.|:|| ...|....||:. .
Mouse   544 ----YGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLP-SHISEHGRDFLR-R 602

  Fly   288 LQKEYMARPNYEQLLKHSF 306
            :..|...||:.|:||.|.|
Mouse   603 IFVEARQRPSAEELLTHHF 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	81/284 (29%)
Map3k3	NP_036077.1	PB1_Mekk2_3	45..123	CDD:99726
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..184
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..273
		STKc_MEKK3_like	361..621	CDD:270795	79/277 (29%)