Protein Alignment lic and Map2k2

DIOPT Version :10

• Sequence 1: NP_477162.1
• Gene: lic / 32257
• FlyBaseID: FBgn0261524
• Length: 334
• Species: Drosophila melanogaster
• Sequence 2: NP_075627.2
• Gene: Map2k2 / 26396
• MGIID: 1346867
• Length: 401
• Species: Mus musculus
• Alignment Length: 341
• Identity: 114/341 - (33%)
• Similarity: 183/341 - (53%)
• Gaps: 59/341 - (17%)

  Fly    40 DIDADSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPY 104
            ::..|..|:|.:||.|..|:|.|.||:.:..::|.|.|.:.:....:::::.:|.: :...:.||
Mouse    66 ELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQV-LHECNSPY 129

  Fly   105 TVHFYGAMYREGDVWICMEVM-STSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKV 168
            .|.||||.|.:|::.||||.| ..|||    :|.....|:.|.:|||::::|:..|.||..:.::
Mouse   130 IVGFYGAFYSDGEISICMEHMDGGSLD----QVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQI 190

  Fly   169 IHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNPAQYDIRSDV 233
            :||||||||||:|..|::|:||||:||.|:||:|.:. .|.:.||:|||:  ||  ..|.::||:
Mouse   191 MHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSF-VGTRSYMSPERL--QG--THYSVQSDI 250

  Fly   234 WSLGIGMIEMATGRYPY----------------------------DNWRTP-------------- 256
            ||:|:.::|:|.||||.                            ...|.|
Mouse   251 WSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISVGHGMDSRP 315

  Fly   257 ----FEQLRQVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPNYEQLLKHSFIVEHLQRNTDI 317
                ||.|..:|.:.||:||.|.||.:|::|:..||.|....|.:.:.|:.|:||........|.
Mouse   316 AMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLMNHAFIKRSEGEEVDF 380

  Fly   318 SEFVARILDLPDAQPA 333
            :.::.|.|.|  .||:
Mouse   381 AGWLCRTLRL--KQPS 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	110/328 (34%)
Map2k2	NP_075627.2	PKc_MEK	70..388	CDD:132946	110/327 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..310		2/27 (7%)