DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lic and pek1

DIOPT Version :9

Sequence 1:	NP_477162.1	Gene:	lic / 32257	FlyBaseID:	FBgn0261524	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_596795.1	Gene:	pek1 / 2540919	PomBaseID:	SPBC543.07	Length:	363	Species:	Schizosaccharomyces pombe

Alignment Length:	367	Identity:	128/367 - (34%)
Similarity:	184/367 - (50%)	Gaps:	50/367 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSKRHRLTPFTIAKEPEAAIVPPRNLDSRATIQIGDRTF------------------------DI 41
            |||:..|...|.....|..|..|...|::..::|.|..|                        ::
pombe     1 MSKKPVLNLDTSNGFSEEYISHPERNDNQGIVEITDLVFSSESKLTQRKESRDSKTFVPSFLEEL 65

  Fly    42 DADSLEKIC---------DLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISM 97
            |.|.|.::.         .||.|..|.|.|.|.:.|..:.|:|.:....|...|.:|:.:|.|:
pombe    66 DDDHLHELVTNGGILYMNSLGEGVSGSVRKCRIRGTQMIFAMKTVLAAPNTALQKQLLRELKIN- 129

  Fly    98 RSSDCPYTVHFYGAMYR--EGDVWICMEVMST-SLDKFYPKVFLHDLRMEESVLGKIAMSVVSAL 159
            ||...||.|.:|||.|.  |..:.|.||.... |||..|.:|.....|..|..|||||..|:|.|
pombe   130 RSCTSPYIVKYYGACYNNAECQLNIAMEYCGAGSLDAIYKRVRSQGGRTGERPLGKIAFGVLSGL 194

  Fly   160 HYLHAQLKVIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPYMAPERIDPQGNP 224
            .|||.: |:||||:||||||:...||||:||||:||.||:|:|.|. .|...|||||||    :.
pombe   195 SYLHDR-KIIHRDIKPSNILLTSKGQVKLCDFGVSGELVNSLAGTF-TGTSYYMAPERI----SG 253

  Fly   225 AQYDIRSDVWSLGIGMIEMATGRYPYDNWRT----PFEQLRQVVEDSPPRLPEG---TFSPEFED 282
            ..|.|.||:||||:.::|:|..|:|:....:    |.|.|..::...||.||:.   .:|..|:.
pombe   254 GSYTISSDIWSLGLTLMEVALNRFPFPPEGSPPPMPIELLSYIINMPPPLLPQEPGIKWSKSFQH 318

  Fly   283 FIAVCLQKEYMARPNYEQLLKHSFIVEHLQRNTDISEFVARI 324
            |:.|||.|:...||..:::|.|.::....:.:.|:.||:.::
pombe   319 FLCVCLDKDKTRRPGPQKMLTHPWVKAFERIHVDMEEFLRQV 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	115/300 (38%)
pek1	NP_596795.1	PKc_Pek1_like	77..361	CDD:270793	113/291 (39%)
pek1	NP_596795.1	Pkinase	85..343	CDD:278497	110/264 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48013
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010