DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lic and sek-5

DIOPT Version :9

Sequence 1:	NP_477162.1	Gene:	lic / 32257	FlyBaseID:	FBgn0261524	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_508916.3	Gene:	sek-5 / 185267	WormBaseID:	WBGene00018034	Length:	360	Species:	Caenorhabditis elegans

Alignment Length:	231	Identity:	87/231 - (37%)
Similarity:	131/231 - (56%)	Gaps:	10/231 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 RIPMTVNIREQHRL----VMDLDISMRSSDCPYTVHFYG---AMYRE-GDVWICMEVMSTSLDKF 132
            |:|..|:....::|    :.::::....:.||:.|||:|   ..||: ..:.|.||.|:.|....
Worm    82 RLPKGVDQDSTNKLMAKKLREVNVINGCAPCPFIVHFFGYYVHKYRDCVKIHIFMEEMALSASVL 146

  Fly   133 YPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLKVIHRDVKPSNILINRAGQVKICDFGISGYL 197
            ..:.......:.|.|:|:|..||:.|:.:|..:|::||||:||.||||:..|:||||||||.|.|
Worm   147 KTEALKQGGAIPEFVIGRIVCSVIHAMWFLKDRLQIIHRDIKPGNILIDYDGRVKICDFGICGIL 211

  Fly   198 VDSIAKTIDAGCKPYMAPE-RIDPQGNPAQYDIRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLR 261
            .:|||.: |.||:.|.||| .:....|...|.|:||:|||||.:.|:||.||||....:.|..|.
Worm   212 ENSIAVS-DTGCQQYTAPEILVKGVSNSPGYSIKSDIWSLGITIFELATLRYPYPVGFSEFTLLS 275

  Fly   262 QVVEDSPPRLPEGTFSPEFEDFIAVCLQKEYMARPN 297
            .:|....|.|..||:|....:|::..||.:...||:
Worm   276 AIVTTPAPYLERGTYSDSLVEFVSKLLQIKEADRPS 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	87/231 (38%)
sek-5	NP_508916.3	PKc_like	58..311	CDD:389743	86/229 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0984
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D688282at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48013
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880