Protein Alignment hep and OXSR1

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: XP_011532633.1
• Gene: OXSR1 / 9943
• HGNCID: 8508
• Length: 580
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 115/450 - (25%)
• Similarity: 180/450 - (40%)
• Gaps: 88/450 - (19%)

  Fly   204 GNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPD 268
            |:|.:..|...........:|:|::...........:|.::..:.:.|. ..||.....||...:
Human    77 GSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHH-PNIVSYYTSFVVKDE 140

  Fly   269 VWICMELMSMCFDKLLKLSKKPVPE-----QILGKVTVATV-----NALSYLKDKHGVIHRDVKP 323
            :|:.|:|:|  ...:|.:.|..|.:     .:|.:.|:||:     ..|.|| .|:|.||||||.
Human   141 LWLVMKLLS--GGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYL-HKNGQIHRDVKA 202

  Fly   324 SNILIDERGNIKLCDFGIS------GRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSL 382
            .|||:.|.|::::.|||:|      |.:..:|......|...:||||.::..: .||.:||:||.
Human   203 GNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVR-GYDFKADIWSF 266

  Fly   383 GITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEG-----YNFSQQFRDFVIKCLTKNHQ 442
            |||.:||||..:||.. ....:||...|.::||.|..|..     ..:.:.||..:..||.|:.:
Human   267 GITAIELATGAAPYHK-YPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPE 330

  Fly   443 DRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQRATATGS------AIGSGAG 501
            .||...|||...|              ||..|:.....  :.|||||.....      .:...:|
Human   331 KRPTAAELLRHKF--------------FQKAKNKEFLQ--EKTLQRAPTISERAKKVRRVPGSSG 379

  Fly   502 SLAGSGSG-------SAGGAVKYGRATTYAGQSP--------------TNPQKTI--KPTQIPSY 543
            .|..:..|       ......:.|:|.....:||              |:|..|:  .|.||.::
Human   380 RLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAH 444

  Fly   544 QQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLS 603
            ..|.:.......||:....|..|..|....                .:||||..:..|:|
Human   445 LPQPAGQIATQPTQVSLPPTAEPAKTAQAL----------------SSGSGSQETKIPIS 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	85/292 (29%)
OXSR1	XP_011532633.1	STKc_OSR1_SPAK	77..344	CDD:270787	82/286 (29%)
		OSR1_C	487..544	CDD:463491	0/1 (0%)