Protein Alignment hep and Stk4

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_067395.1
• Gene: Stk4 / 58231
• MGIID: 1929004
• Length: 487
• Species: Mus musculus
• Alignment Length: 480
• Identity: 125/480 - (26%)
• Similarity: 213/480 - (44%)
• Gaps: 90/480 - (18%)

  Fly   191 PTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKY 255
            |.::.|:  |..||.|:.|:|.|.:|..:..|:|:||:....:.:|   |:.::. :::..|..:
Mouse    26 PEEVFDV--LEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE---IIKEIS-IMQQCDSPH 84

  Fly   256 IVKCLGCFVRDPDVWICMELMSM-CFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGV--I 317
            :||..|.:.::.|:||.||.... ....:::|..|.:.|..:..:..:|:..|.||   |.:  |
Mouse    85 VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYL---HFMRKI 146

  Fly   318 HRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSA-GCAAYMAPERIDPKKPKYDIRADVWS 381
            |||:|..|||::..|:.||.|||::|:|.|:.|...:. |...:||||.|  ::..|:..||:||
Mouse   147 HRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI--QEIGYNCVADIWS 209

  Fly   382 LGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPK 446
            ||||.:|:|..:.||...: ....:..:..:.||.....|  .:|..|.|||.:||.|:.:.|..
Mouse   210 LGITAIEMAEGKPPYADIH-PMRAIFMIPTNPPPTFRKPE--LWSDNFMDFVKQCLVKSPEQRAT 271

  Fly   447 YPELLAQPFIRIYESAKV--DVPNWFQSIKDNRLRA-----------NGDPTLQRATATGSAIGS 498
            ..:||..||::..:...:  |:.|....:|..|..|           |.:.....:.....|.|.
Mouse   272 ATQLLQHPFVKSAKGVSILRDLINEAMDVKLKRQEAQQREVDQDDEENSEEDEMDSGTMVRAAGD 336

  Fly   499 GAGS--LAGSGSGSAGGAVKYGRATTYAGQSPT---------------NPQKTIKPTQIPSYQQQ 546
            ..|:  :|.:.||.|...:::|  .|...|..|               ...:|::|.: ||:
Mouse   337 EMGTVRVASTMSGGANTMIEHG--DTLPSQLGTMVINTEDEEEEGTMKRRDETMQPAK-PSF--- 395

  Fly   547 QSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPSAG--- 608
             .::|.|...:          ...|.||               .|.|||..::|....|..|
Mouse   396 -LEYFEQKEKE----------NQINSFG---------------KNVSGSLKNSSDWKIPQDGDYE 434

  Fly   609 ------IGDL-NRLYRKSPFMQRKL 626
                  :.|| .||....|.|::::
Mouse   435 FLKSWTVEDLQKRLLALDPMMEQEM 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	89/290 (31%)
Stk4	NP_067395.1	STKc_MST1_2	26..281	CDD:132943	85/268 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..334		2/28 (7%)
		SARAH_MST1	432..480	CDD:439181	6/28 (21%)