Protein Alignment hep and Stk3

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_062609.2
• Gene: Stk3 / 56274
• MGIID: 1928487
• Length: 497
• Species: Mus musculus
• Alignment Length: 298
• Identity: 96/298 - (32%)
• Similarity: 159/298 - (53%)
• Gaps: 26/298 - (8%)

  Fly   164 PPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQM 228
            ||.|::  |||.:.|.      :..:.|.::.|:  |..||.|:.|:|.|.:|..|..::|:||:
Mouse     4 PPASKS--KLKKLSED------SLTKQPEEVFDV--LEKLGEGSYGSVFKAIHKESGQVVAIKQV 58

  Fly   229 RRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSM-CFDKLLKLSKKPVP 292
            ....:.:|   |:.::. :::..|..|:||..|.:.::.|:||.||.... ....:::|..|.:.
Mouse    59 PVESDLQE---IIKEIS-IMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLT 119

  Fly   293 EQILGKVTVATVNALSYLKDKHGV--IHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSA 355
            |..:..:..:|:..|.||   |.:  ||||:|..|||::..|:.||.|||::|:|.|:.|...:.
Mouse   120 EDEIATILKSTLKGLEYL---HFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTV 181

  Fly   356 -GCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPY 419
             |...:||||.|  ::..|:..||:||||||.:|:|..:.||...: ....:..:..:.||....
Mouse   182 IGTPFWMAPEVI--QEIGYNCVADIWSLGITSIEMAEGKPPYADIH-PMRAIFMIPTNPPPTFRK 243

  Fly   420 GEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIR 457
            .|  .:|..|.|||.|||.|:.:.|....:||..|||:
Mouse   244 PE--LWSDDFTDFVKKCLVKSPEQRATATQLLQHPFIK 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	89/281 (32%)
Stk3	NP_062609.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		7/23 (30%)
		STKc_MST1_2	23..278	CDD:132943	87/268 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..343
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	368..394
		SARAH_MST2	442..490	CDD:439182