Protein Alignment hep and map2k7

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_001177235.1
• Gene: map2k7 / 560913
• ZFINID: ZDB-GENE-090312-186
• Length: 438
• Species: Danio rerio
• Alignment Length: 484
• Identity: 243/484 - (50%)
• Similarity: 296/484 - (61%)
• Gaps: 77/484 - (15%)

  Fly     1 MSTIEFETIGSRLQSLEAKLQAQN-ESHDQIVLSGARGPVVSGSVPSARVPPLATSASAATSATH 64
            ||::|     .||..:|.||:.:| |:..:|.|:      :..|....|..|:..   ...|...
Zfish     1 MSSLE-----QRLSRIEEKLKQENKEARKRIDLN------IDMSPQRTRPRPIIV---IQLSPAP 51

  Fly    65 APSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAAPATGTFGGTYTPPTTR 129
            |||              ||.|..:|.|...||.|:||.||
Zfish    52 APS--------------QRAALQLPLANDGGSRSSSSESS------------------------- 77

  Fly   130 VSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHP-----PVSETDMKLKIIMEQTGKLNINGRQ 189
                    |...|.|    ||.|. :|.|||.|:.     ..:|.|.||:.||:|||.|.|:|::
Zfish    78 --------PQHPSYP----NRPRQ-MLTLPTTPYNLQKNLENAEIDQKLQEIMKQTGYLKIDGQR 129

  Fly   190 YPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCK 254
            ||.::.||...|::|:||.|.|.|:....:..:|||||||||||.:||||||||||||||||||.
Zfish   130 YPAEVTDLISEGEIGSGTCGQVFKVRFKKTGHVIAVKQMRRTGNKDENKRILMDLDVVLKSHDCP 194

  Fly   255 YIVKCLGCFVRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHR 319
            ||::|.|..|.:.||:|.||||..|.:||.|..:.|:||.||||:|||.||||.|||:|||||||
Zfish   195 YIIQCYGAIVTNTDVFIAMELMGTCAEKLKKRIQGPIPEAILGKMTVAIVNALLYLKEKHGVIHR 259

  Fly   320 DVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERI---DPKKPKYDIRADVWS 381
            ||||||||:|.:|.|||||||||||||||||.|||||||||||||||   ||.||.|||||||||
Zfish   260 DVKPSNILLDAKGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPSKPDYDIRADVWS 324

  Fly   382 LGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPK 446
            |||:||||||.:.||:.|.||||||||||..:||.||...|  ||..|:.||..||||:|:.|||
Zfish   325 LGISLVELATGQFPYKNCKTDFEVLTKVLQEDPPVLPLSMG--FSPDFQSFVKDCLTKDHRKRPK 387

  Fly   447 YPELLAQPFIRIYESAKVDVPNWFQSIKD 475
            |.:||...|||.||.::|||..|||::.:
Zfish   388 YHKLLEHSFIRRYEVSEVDVAGWFQAVME 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	193/298 (65%)
map2k7	NP_001177235.1	PKc_MKK7	121..417	CDD:270791	193/298 (65%)