Protein Alignment hep and MAP2K3

DIOPT Version :9

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_659731.1
• Gene: MAP2K3 / 5606
• HGNCID: 6843
• Length: 347
• Species: Homo sapiens
• Alignment Length: 322
• Identity: 143/322 - (44%)
• Similarity: 198/322 - (61%)
• Gaps: 20/322 - (6%)

  Fly   157 PLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNT 221
            |.||||....|.|            .:.|..|.:..:.:||..:.:||.|..|.|.|:.|..|.|
Human    36 PNPTPPRNLDSRT------------FITIGDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGT 88

  Fly   222 IIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLK- 285
            |:|||::|.|.|::|.||:|||||:.:::.||.|.|...|...|:.|||||||||....||..:
Human    89 IMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRK 153

  Fly   286 -LSKK-PVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDS 348
             |.|. .:||.|||::.|:.|.||.:|..|..||||||||||:||::.|::|:|||||||.||||
Human   154 VLDKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDS 218

  Fly   349 KANTRSAGCAAYMAPERIDPK--KPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLD 411
            .|.|..|||..|||||||:|:  :..|::::||||||||::|:|..|.|||...|.|:.|.:|::
Human   219 VAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVE 283

  Fly   412 SEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSI 473
            ...|.||   ...||.:|.||..:||.||..:|..|.||:..||..::::.|.|:..:.:.|
Human   284 EPSPQLP---ADRFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEI 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	136/298 (46%)
MAP2K3	NP_659731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46		5/9 (56%)
		PKc_MKK3_6	62..344	CDD:173729	134/284 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920