Protein Alignment hep and map2k5

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: XP_017947570.1
• Gene: map2k5 / 549042
• XenbaseID: XB-GENE-960353
• Length: 474
• Species: Xenopus tropicalis
• Alignment Length: 355
• Identity: 119/355 - (33%)
• Similarity: 182/355 - (51%)
• Gaps: 53/355 - (14%)

  Fly   162 PHPPVSETDMKLKIIMEQTGKLNINGRQYPTDI--NDLKHLGDLGNGTSGNVV------------ 212
            |..|.:.....||....:..|:..||:....||  .|:     ||:|..|.|.
 Frog   134 PSVPDNIAGNSLKKSSAELKKILANGQINELDIQCRDI-----LGHGNGGTVYNWPIFAMSIGRT 193

  Fly   213 --------------KMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCF 263
                          |..|:.|..|:|||.:......|..::|:.:|:::.|. |..||:...|.|
 Frog   194 SEDLDKGPCRRIMGKAYHVPSGKILAVKVIPLDITVELQRQIMSELEILYKC-DSLYIIGFYGAF 257

  Fly   264 VRDPDVWICMELMSMCFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILI 328
            ..:..:.||.|.|.   ...|.:.:| :|||:||::.||.:..|:||.... ::||||||||:|:
 Frog   258 FVENRISICTEFMD---GGSLDVYRK-IPEQVLGRIAVAVLKGLTYLWSLK-ILHRDVKPSNMLV 317

  Fly   329 DERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELATAR 393
            :.||::||||||:|.:||:|.|.| ..|..||||||||..:  :|.|.:|||||||:.:|||..|
 Frog   318 NTRGHVKLCDFGVSTQLVNSIAKT-YVGTNAYMAPERIAGE--QYGIHSDVWSLGISFMELALGR 379

  Fly   394 SPY------EGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLA 452
            .||      .|.....::|..::|.|.|.||.||   ||:.|..|:.:|:.|..::||...||:.
 Frog   380 FPYPQIQKNHGSLMPLQILQCIVDEECPVLPLGE---FSESFVHFITQCMRKPPKERPAPEELMD 441

  Fly   453 QPFIRIYESAKVD-VPNWF-QSIKDNRLRA 480
            .|||..:.....: |..|. :::::.|:::
 Frog   442 HPFIVQFNDGNTEAVSMWVCRALEERRMQS 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	114/330 (35%)
map2k5	XP_017947570.1	PB1_Map2k5	17..107	CDD:99717
		PKc_MKK5	164..468	CDD:132950	111/320 (35%)