Protein Alignment hep and map2k6

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_001005653.1
• Gene: map2k6 / 448132
• XenbaseID: XB-GENE-944183
• Length: 335
• Species: Xenopus tropicalis
• Alignment Length: 353
• Identity: 150/353 - (42%)
• Similarity: 208/353 - (58%)
• Gaps: 36/353 - (10%)

  Fly   126 PTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIMEQTGKLNINGRQY 190
            |..::.:.....|.:||                ||||.    :.|.|..|:        |..:.:
 Frog    11 PGLKIPKEAFDQPQVSS----------------PTPPR----DLDSKACIL--------IGEKNF 47

  Fly   191 PTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKY 255
            ....:||:.:.:||.|..|.|.||.|:.|..|:|||::|.|.|::|.||:|||||:.:::.||.:
 Frog    48 EVKADDLEPIEELGRGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCHF 112

  Fly   256 IVKCLGCFVRDPDVWICMELMSMCFDKLLK--LSK-KPVPEQILGKVTVATVNALSYLKDKHGVI 317
            .|...|...|:.|||||||||....||..|  :.| ..:||.||||:.|:.|.||.:|..|..||
 Frog   113 TVTFYGALFREGDVWICMELMDTSLDKFYKNVIDKGLTIPEDILGKIAVSIVRALEHLHSKLSVI 177

  Fly   318 HRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPK--KPKYDIRADVW 380
            ||||||||:||::.|.:|:|||||||.||||.|.|..|||..|||||||:|:  :..|.:::|:|
 Frog   178 HRDVKPSNVLINKEGQVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYSVKSDIW 242

  Fly   381 SLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRP 445
            ||||||:|||..|.||:...|.|:.|.:|::...|.||..:   ||.:|.||..|||.||.::||
 Frog   243 SLGITLIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADK---FSAEFVDFTSKCLKKNSKERP 304

  Fly   446 KYPELLAQPFIRIYESAKVDVPNWFQSI 473
            .||||:...|..::||...||.::.:.|
 Frog   305 TYPELMQHHFFVLHESKNTDVASFVKRI 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	139/298 (47%)
map2k6	NP_001005653.1	PKc_MKK3_6	52..334	CDD:173729	138/284 (49%)