Protein Alignment hep and GckIII

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_650596.1
• Gene: GckIII / 42064
• FlyBaseID: FBgn0266465
• Length: 642
• Species: Drosophila melanogaster
• Alignment Length: 727
• Identity: 188/727 - (25%)
• Similarity: 286/727 - (39%)
• Gaps: 197/727 - (27%)

  Fly   203 LGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLD---VVLKSHDCKYIVKCLGCFV 264
            :|.|:.|.|.|.:...:..::|:|.:    :.||.:..:.|:.   :||...|..|:.|..|.|:
  Fly    19 IGKGSFGEVFKGIDNRTQQVVAIKII----DLEEAEDEIDDIQQEIMVLSQCDSPYVTKYYGSFL 79

  Fly   265 RDPDVWICMELMSMCFDKLLKLSKKPVPEQI-LGKVTVATVNALSYLKDKHGVIHRDVKPSNILI 328
            :...:||.||.:.  ....|.|.|....|:: :|.:....:..|.||..:. .:|||:|.:|:|:
  Fly    80 KGTKLWIIMEYLG--GGSALDLMKAGSFEEMHIGIILREVLKGLDYLHSER-KLHRDIKAANVLL 141

  Fly   329 DERGNIKLCDFGISGRLVD--SKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITLVELAT 391
            .|:|::||.|||::|:|.:  ||.|| ..|...:||||.|  |:.:||.:||:||||||.:|||.
  Fly   142 SEQGDVKLADFGVAGQLTNTTSKRNT-FVGTPFWMAPEVI--KQSQYDAKADIWSLGITAIELAK 203

  Fly   392 ARSPYEGCNTD---FEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQ 453
            ...|    |::   ..||..:..:.||.|.    .::::.|:|||..||.|:.::||...|||..
  Fly   204 GEPP----NSELHPMRVLFLIPKNNPPQLT----GSYTKSFKDFVEACLNKDPENRPTAKELLKY 260

  Fly   454 PFIRIYESAK-----VDVPNWFQSIKDNRLRANGDPTLQRATATGSAIGSGAGSLAGSGSGSAGG 513
            |||:   .||     :|:.:.|:..|                     :..|..|...|.:..:..
  Fly   261 PFIK---KAKKNAYLIDLIDRFKKWK---------------------VSKGDESETESENSDSDS 301

  Fly   514 AVKYGRATTYAGQSPTNPQ-KTIKPTQI--------PSYQQQQSQFFMQSATQLPQTTTTTPTAT 569
            ..|.|      |.|...|. .|:|...|        .|:|.|:.:..||...|    ||.:|
  Fly   302 DAKQG------GSSQDEPWIMTVKGLHINSAPRAGVNSFQLQEHELTMQKLMQ----TTHSP--- 353

  Fly   570 TNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPSAGIGDLNRLYRKSPFMQRKLSNGSHHPH 634
                     ..|.|..:..:.|...||.||...|..|..:...|.....:..:..:.|:..:|.|
  Fly   354 ---------AGGGGVQASPAANALSSSVSAVAASASSVSVITANEGVSSASALPPQNSHVHNHNH 409

  Fly   635 YKYNDESPKKESMFSSIGQSILRNLTTSPFSQKKHNSTATTIPLPHNNQTLITDAATAAAAAATA 699
            ...|:.:              :|||:         |..|||..|                   .|
  Fly   410 NNINNNN--------------IRNLS---------NKHATTTML-------------------NA 432

  Fly   700 TTPPNIAATVLTTTPTTTPTWRLPTENSQAYDSCDSSSNATTTTLNLGLSSPSPSLPRKQFPTES 764
            ..||:                           |..|||:|  :.|....||..|.|  :|..:.:
  Fly   433 APPPS---------------------------SVTSSSSA--SELQQKRSSSKPEL--RQSRSAA 466

  Fly   765 PTLQLTSQQQQQPQRLQPGNQSPIVLQRFYHQQNQLREKEAAERYQQQRQQPPVGVTSTNPFHSN 829
            |..|:..::......||....:|                ..||:.||:|.      :....||:|
  Fly   467 PLDQVEDRRASLGLPLQSSVPTP----------------STAEQQQQRRS------SQRESFHAN 509

  Fly   830 YVPPPPSTHSTSSQSSTQSTCSQIAINPASISPSSGSG----TGNMAGLGIGSAPA--------S 882
            ..   ....|.||.|:..|....:|.|.||....||:|    ..|.|.|.....|.        |
  Fly   510 NA---ALVASCSSSSNNHSHEEHVATNHASHVKHSGAGQRLVQTNSACLNNFLFPVLSDIQRKYS 571

  Fly   883 GLGAAGHFGAGG 894
            |.|:||..|:||
  Fly   572 GGGSAGSGGSGG 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	95/286 (33%)
GckIII	NP_650596.1	STKc_MST3_like	12..283	CDD:270786	94/284 (33%)