Protein Alignment hep and Mkk4

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_477353.1
• Gene: Mkk4 / 41020
• FlyBaseID: FBgn0024326
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 441
• Identity: 182/441 - (41%)
• Similarity: 243/441 - (55%)
• Gaps: 60/441 - (13%)

  Fly    47 ARVPPLATSASAATSATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFAS 111
            :|.||...|.: ..|..|.||..:.:.|||               |..||:|:|..:.....|.:
  Fly    16 SRNPPDQLSLN-NLSIRHPPSSTSSTSSGS---------------TSSGSSSSSQHNHVTRCFGA 64

  Fly   112 AAPATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKII 176
            ..|       ..|||.  .|...|.:|..||......:|.|                      |.
  Fly    65 QQP-------QQTPPV--ASSQVPPVPAASSSSAADRHRER----------------------IR 98

  Fly   177 MEQTGKLNI-----NGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEE 236
            .:..|||..     |...:.:|  ||:..|::|.|..|.|.||.....:.::|||::|.|.:.:|
  Fly    99 QQACGKLQFGEGGANTHTFTSD--DLEDEGEIGRGAFGAVNKMTFKKLDKVMAVKRIRSTVDEKE 161

  Fly   237 NKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLKL----SKKPVPEQILG 297
            .|::||||:||:||::|.|||:..|...::.|.|||||||....||..|.    .::.:||.||.
  Fly   162 QKQLLMDLEVVMKSNECIYIVQFYGALFKEGDCWICMELMDTSLDKFYKYIYEKQQRHIPESILA 226

  Fly   298 KVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMA 362
            |:||||||||:|||::..:|||||||||||:..||:||||||||||:||||.|.|:.|||..|||
  Fly   227 KITVATVNALNYLKEELKIIHRDVKPSNILLHRRGDIKLCDFGISGQLVDSIAKTKDAGCRPYMA 291

  Fly   363 PERIDPKKPK-YDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPP-CLPYGEGYNF 425
            ||||||::.| ||:|:|||||||||:|:||...||...::.||.|.:|:..||| .|....|..|
  Fly   292 PERIDPERAKGYDVRSDVWSLGITLMEVATGNFPYRKWDSVFEQLCQVVQGEPPRLLTSYNGMEF 356

  Fly   426 SQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDN 476
            |::|.|||..||.|...|||||..||..||||..|::..||..:...|.::
  Fly   357 SKEFVDFVNTCLIKKESDRPKYSRLLEMPFIRRGETSHTDVAVYVADILES 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	153/305 (50%)
Mkk4	NP_477353.1	PKc_MKK4	115..405	CDD:270790	148/291 (51%)