Protein Alignment hep and stk4

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_989249.1
• Gene: stk4 / 394860
• XenbaseID: XB-GENE-955920
• Length: 485
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 128/527 - (24%)
• Similarity: 231/527 - (43%)
• Gaps: 113/527 - (21%)

  Fly   173 LKIIMEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEEN 237
            ||.:.|::  ||    :.|.::.|:  |..||.|:.|:|.|..|..::.|:|:||:....:.:|
 Frog    14 LKKLSEES--LN----KQPEEVFDV--LEKLGEGSYGSVYKASHKETSQIVAIKQIPVESDLQE- 69

  Fly   238 KRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMC----FDKLLKLSKKPVPEQILGK 298
              |:.:: .:::..|..::||..|.:.::.|:||.||   .|    ...:::|.|:.:.|.....
 Frog    70 --IIKEI-AIMQQCDSLHVVKYYGSYFKNTDLWIVME---FCGGGSISDIIRLRKQTLKEDETAT 128

  Fly   299 VTVATVNALSYLKDKHGV--IHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSA-GCAAY 360
            :..:|:..|.||   |.:  ||||:|..|||::..|..||.|||::|:|.|:.|...:. |...:
 Frog   129 ILQSTLKGLEYL---HFMRKIHRDIKAGNILLNSEGTAKLADFGVAGQLTDTMAKRNTVIGTPFW 190

  Fly   361 MAPERIDPKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNF 425
            ||||.|  ::..|:..||:||||||.:|:|..:.||...: ....:..:..:.||.....|  .:
 Frog   191 MAPEVI--QEIGYNCVADIWSLGITAIEMAEGKPPYAEIH-PMRAIFMIPSNPPPTFRKPE--LW 250

  Fly   426 SQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLR----------- 479
            |:.|.||:..||.||.:.|....|||..|||:..:...: :.:.....:|.:|:
 Frog   251 SKDFVDFINLCLVKNPELRSSATELLQHPFIKTAKGESI-LRHLINEAQDAKLKRTELKQREVEP 314

  Fly   480 ---ANGDPTLQRATATGSAIGSGAGSL------AGSGSGSAGGAVKYGRATTYAG---------- 525
               .|.|   :.....|:.:.:|:..|      :.....:....|:..:..|..|
 Frog   315 EEEENAD---EDEADVGTMVQAGSKDLNTMKEFSTMNEAADCTMVEKDKLNTQMGTMLINDEDEE 376

  Fly   526 -----QSPTNPQKTIKPTQIPSYQQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNG 585
                 :..|.|.:..||:.:..::|:::||      ..|:.||..|:
 Frog   377 ETGTMKQCTEPVQPAKPSFLEYFEQKENQF------GTPEKTTPAPS------------------ 417

  Fly   586 SGGSGNGSGSSSSASPLSPPSAGIGDLN------RLYRKSPFMQRKLSNGSHHPHYKYNDESPKK 644
                   :..|....||:...:.:.|.:      ||....|.|::::    ...|:||   ..|:
 Frog   418 -------TDPSEWKIPLNGDYSFLKDWSVTELQLRLNSLDPMMEQEI----EEIHHKY---QAKR 468

  Fly   645 ESMFSSI 651
            :.:..:|
 Frog   469 QPILEAI 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	91/301 (30%)
stk4	NP_989249.1	STKc_MST1_2	26..281	CDD:132943	87/271 (32%)
		SARAH_MST1	430..478	CDD:439181	10/53 (19%)