Protein Alignment hep and hppy

DIOPT Version :9

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Alignment Length: 1245
• Identity: 266/1245 - (21%)
• Similarity: 429/1245 - (34%)
• Gaps: 352/1245 - (28%)

  Fly   188 RQYPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHD 252
            |:.|.|..:|  :..:|:||.|:|.|...:.||.:.|:|.::    .|.:..|.:....::...|
  Fly    19 RRNPQDEYEL--IQKIGSGTYGDVYKAKRIQSNELAAIKVIK----LEPSDDIQIIQQEIIMMRD 77

  Fly   253 CKY--IVKCLGCFVRDPDVWICMELMSMC----FDKLLKLSKKPVPEQILGKVTVATVNALSYLK 311
            |::  |:...|.::|...:|||||   .|    ...:.::: .|:.|..:..:...|:..|.||.
  Fly    78 CRHPNIIAYYGSYLRRDKLWICME---FCGGGSLQDIYQVT-GPLTEVQIAYMCRETLKGLEYLH 138

  Fly   312 DKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSA--GCAAYMAPE-RIDPKKPKY 373
            .. |.:|||:|.:|||:.|.|::||.|||:|.: :.:..|.|.:  |...:|||| ....:|..|
  Fly   139 SM-GKMHRDIKGANILLTEYGDVKLADFGVSAQ-ITATINKRKSFIGTPYWMAPEVAAVERKGGY 201

  Fly   374 DIRADVWSLGITLVELATARSPYEGCNTDFEV-------LTKVLDSEPPCLPYGEGYNFSQQFRD 431
            :...|:|:.|||.:|||..:.|.      |::       |......:||.|...:  .:|..|.:
  Fly   202 NQLCDIWACGITAIELAELQPPM------FDLHPMRALFLMSKSGFKPPTLNNKD--KWSPTFHN 258

  Fly   432 FVIKCLTKNHQDRPKYPELLAQPFIRIYESAKV----------DVPNWFQSIKDNRLRANGDPTL 486
            |:...||||.:.||....||..||::...|.:|          ..|.::..:..:.....|.|
  Fly   259 FIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVP-- 321

  Fly   487 QRATATGSAIGSGAGSLAGSGSGSAGGAVKYGRATTYAGQSPTNPQKTIKPTQIPSYQQQQSQFF 551
            ||       |.|...|.. :|..:....:|.|..|.......::..:|: |:.:...|....:..
  Fly   322 QR-------IASKMTSRT-NGVPAQNHTLKTGMTTNSTWNERSSSPETL-PSDMSLLQYIDEELK 377

  Fly   552 MQSATQLPQTTTTTPTATTNC------FGGSGNGNGRGNGSGG-SGNGSGSSSSASPLSPPSAGI 609
            :::...|...|.....|..:|      ..|.|.|.|.|.|:|| :.|||.|||.       .|.:
  Fly   378 LRATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSG-------GATV 435

  Fly   610 GDLNRLYRKSPFMQRKLSNGSHHPHYKYNDES---PKKESMFSSIGQSILRNLTTSPFSQKKHNS 671
            |..:..:::.       ....|||::.:..:|   |:::...|            ...:|::|:.
  Fly   436 GTTHHQHQQH-------HQHHHHPNHLHQHQSHQLPQQQQQQS------------HQAAQQEHHH 481

  Fly   672 TATTIPLPHNNQT------LITDAATAAAAAATATTPPNIAATVLTTTPTTTPTWRLPTENSQAY 730
                    |:..|      |:|..|...:::|:..:.|.::|.:...:       .:.......:
  Fly   482 --------HHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGMRS-------HVVGHMGMGF 531

  Fly   731 DSCDSSSNATTTTLNLGLSSPSPSLPRKQFPTESPTLQLTSQQQQQPQRLQPGNQS--------- 786
            ......||..||:::                .:...|..............|||.|
  Fly   532 GMGLGMSNLRTTSID----------------ADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSG 580

  Fly   787 -PIVLQRFYHQQNQLREKEAAERYQQQRQQPPVGVTS-TNPFHSNYVPPPPSTHSTSSQSSTQST 849
             ......:....:..|...||:  ..|...|.|...| :|..|.:    .|.|.|.||.:|:.|.
  Fly   581 CSASAAHYLRYSSNYRSAAAAQ--ASQAAHPHVNSNSNSNNGHGH----APITSSISSSASSASF 639

  Fly   850 CSQIAINPASISPSSGSGTGNMAGLGIGSAPASGLGAAGHFGAGGTGEQLQYQPLPIAAEATGTS 914
            .:::.:    :..|||...  :.|.|.||:..|..|.|.. |..|..::.:...||.||..:...
  Fly   640 YNRLLL----LDNSSGDAV--VGGNGGGSSNISSSGGASS-GTNGLLDKHELDALPQAATKSAGD 697

  Fly   915 PTLQSRSPEQQSDYGGNGNM-----VASKLSKLYARRQLLGQSSSSGASNSSLDGCSREQHDAGW 974
            ....|.||...|..|..|:.     .:|..|.||  :.||..||....:.||..|.:.:......
  Fly   698 GFSHSNSPTANSGAGATGSRDNDGPSSSNSSHLY--QNLLRSSSGETPAGSSSAGNNCDYRHENN 760

  Fly   975 FNTLAGAMKRQFATYVKTQLNSTATSPVASSMDRDQEPVHPQPPAYRSVVNNGSGGKSYYYRTLS 1039
            .|.|..:.:|.                  ||||:           ...::.|
  Fly   761 QNGLEDSPRRH------------------SSMDQ-----------LIGLLEN------------- 783

  Fly  1040 AASSSSNTSQSTSPTTEPLPGGGTSSFLRRYASSGPGGSISTPPSPHILAGLDRRHRSPDPPPRY 1104
                     ...||.|..|..|||.........:.|....:|||.|.     .|.|:....|||
  Fly   784 ---------MGKSPRTRSLSDGGTQDDDEAEKEAQPDLLNNTPPVPP-----KRSHKRRHTPPR- 833

  Fly  1105 NRGQSPLLLRKNLLELSGQPPGSPLLHRRYVSASPPLPPPRRG---SESVPGSPQHFRTRIHYT- 1165
                               |..:.|         ||.|....|   |:...|.|    .|:|.|
  Fly   834 -------------------PISNGL---------PPTPKVHMGACFSKIFNGCP----LRVHCTA 866

  Fly  1166 ----PEPQRRIYRTIDQXVALQIMVMXCWYGFDDDAADAAVHDDNQDE----EVGLLEP------ 1216
                ||       |.||.:.:              .|:..:::.|.:|    .:..|.|
  Fly   867 SWIHPE-------TRDQHLLI--------------GAEEGIYNLNMNELHDAAIDQLFPRRTTWL 910

  Fly  1217 ----------------------ISLPVSSAVGDSLSMPAYAGGLGTRLSGAERRIGDRRTC---- 1255
                                  ::|.....|..||.|......|..|......::.|.:.|
  Fly   911 YVIKDVLMSLSGKSCQLYRHDLVALHSKQTVRFSLHMNKIPERLVPRKFALTTKVPDTKCCTQCC 975

  Fly  1256 ---------------SASGSYSSLYTD---------KDEWPGGS-SGGASG------------TS 1283
                           :.||.:...:.|         :.|||..| .||..|            ..
  Fly   976 VTRNPYNGYKYLCGATPSGIFLMQWYDPLNKFMLLKQCEWPAISIQGGGHGCVQNGHTPVFEMII 1040

  Fly  1284 TTRAGYPWTC 1293
            |....||..|
  Fly  1041 TPELEYPIVC 1050

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	88/313 (28%)
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	81/277 (29%)
		S_TKc	26..283	CDD:214567	81/276 (29%)
		CNH	869..1184	CDD:279162	33/203 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910