Protein Alignment hep and Stk4

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_001101270.1
• Gene: Stk4 / 311622
• RGDID: 1312035
• Length: 487
• Species: Rattus norvegicus
• Alignment Length: 485
• Identity: 129/485 - (26%)
• Similarity: 217/485 - (44%)
• Gaps: 100/485 - (20%)

  Fly   191 PTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKY 255
            |.::.|:  |..||.|:.|:|.|.:|..:..|:|:||:....:.:|   |:.::. :::..|..:
  Rat    26 PEEVFDV--LEKLGEGSYGSVYKAIHKETGQIVAIKQVPVESDLQE---IIKEIS-IMQQCDSPH 84

  Fly   256 IVKCLGCFVRDPDVWICMELMSM-CFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGV--I 317
            :||..|.:.::.|:||.||.... ....:::|..|.:.|..:..:..:|:..|.||   |.:  |
  Rat    85 VVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYL---HFMRKI 146

  Fly   318 HRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSA-GCAAYMAPERIDPKKPKYDIRADVWS 381
            |||:|..|||::..|:.||.|||::|:|.|:.|...:. |...:||||.|  ::..|:..||:||
  Rat   147 HRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVI--QEIGYNCVADIWS 209

  Fly   382 LGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPK 446
            ||||.:|:|..:.||...: ....:..:..:.||.....|.:  |..|.|||.:||.|:.:.|..
  Rat   210 LGITAIEMAEGKPPYADIH-PMRAIFMIPTNPPPTFRKPEVW--SDNFMDFVKQCLVKSPEQRAT 271

  Fly   447 YPELLAQPFIRIYESAKV--DVPNWFQSIKDNRLRANGDPTLQRAT-------------ATGS-- 494
            ..:||..||::..:.|.:  |:.|....:|..|..|.     |||.             .:|:
  Rat   272 ATQLLQHPFVKSAKGAAILRDLINEAMDVKLKRQEAQ-----QRAVDQDDDENSEEDEMDSGTMV 331

  Fly   495 -AIGSGAGS--LAGSGSGSAGGAVKYGRATTYAGQSPT---------------NPQKTIKPTQIP 541
             |.|...|:  :|.:.||.|...:::|  .|...|..|               ...:|::|.: |
  Rat   332 RAAGDDMGTVRVASTMSGGANTMIEHG--DTLPSQLGTMVINTEDEEEEGTMKRRDETMQPAK-P 393

  Fly   542 SYQQQQSQFFMQSATQLPQTTTTTPTATTNCFGGSGNGNGRGNGSGGSGNGSGSSSSASPLSPPS 606
            |:    .::|.|...:          ...|.||               .|.|||..::|....|.
  Rat   394 SF----LEYFEQKEKE----------NQINSFG---------------KNVSGSLKNSSDWKIPQ 429

  Fly   607 AG---------IGDL-NRLYRKSPFMQRKL 626
            .|         :.|| .||....|.|::::
  Rat   430 DGDYEFLKSWTVEDLQKRLSALDPMMEQEM 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	90/290 (31%)
Stk4	NP_001101270.1	STKc_MST1_2	26..281	CDD:132943	85/268 (32%)
		SARAH_MST1	432..480	CDD:439181	6/28 (21%)