Protein Alignment hep and Map2k4

DIOPT Version :9

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: XP_038941354.1
• Gene: Map2k4 / 287398
• RGDID: 1307040
• Length: 408
• Species: Rattus norvegicus
• Alignment Length: 435
• Identity: 192/435 - (44%)
• Similarity: 240/435 - (55%)
• Gaps: 62/435 - (14%)

  Fly    62 ATHAPSLGAGSVSGSGISIAQRPAPPVPHATPFGSASASSSSSSASAFASAA------------- 113
            |..:||.|.||..|.|     .|.|..|.|:  |..:.||.......|...|
  Rat     2 AAPSPSGGGGSGGGGG-----TPGPIGPPAS--GHPAVSSMQGFQINFCEKAQSKRKALKLNFAN 59

  Fly   114 -PATGTFGGTYTPPTTRVSRATPTLPMLSSGPGGGLNRTRPVILPLPTPPHPPVSETDMKLKIIM 177
             |...|...|..|.||.|.  .|.:..|         ||..:
  Rat    60 PPVKSTARFTLNPNTTGVQ--NPHIERL---------RTHSI----------------------- 90

  Fly   178 EQTGKLNINGRQ-YPTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRIL 241
            |.:|||.|:..| :.....|||.||::|.|..|:|.||:|..|..|:|||::|.|.:.:|.|::|
  Rat    91 ESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLL 155

  Fly   242 MDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFDKLLK----LSKKPVPEQILGKVTVA 302
            ||||||::|.||.|||:..|...|:.|.||||||||..|||..|    :....:||:||||:|:|
  Rat   156 MDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLA 220

  Fly   303 TVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERID 367
            ||.||::||:...:||||:||||||:|..||||||||||||:||||.|.||.|||..||||||||
  Rat   221 TVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERID 285

  Fly   368 PKKPK--YDIRADVWSLGITLVELATARSPYEGCNTDFEVLTKVLDSEPPCLPYGEGYNFSQQFR 430
            |...:  ||:|:|||||||||.||||.|.||...|:.|:.||:|:..:||.|...|...||..|.
  Rat   286 PSASRQGYDVRSDVWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFI 350

  Fly   431 DFVIKCLTKNHQDRPKYPELLAQPFIRIYESAKVDVPNWFQSIKD 475
            :||..||||:...||||.|||..|||.:||...|:|..:...|.|
  Rat   351 NFVNLCLTKDESKRPKYKELLKHPFILMYEERTVEVACYVCKILD 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	163/302 (54%)
Map2k4	XP_038941354.1	PKc_MKK4	104..394	CDD:270790	156/289 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920