Protein Alignment hep and sek-6

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_509683.1
• Gene: sek-6 / 189074
• WormBaseID: WBGene00012162
• Length: 359
• Species: Caenorhabditis elegans
• Alignment Length: 345
• Identity: 66/345 - (19%)
• Similarity: 119/345 - (34%)
• Gaps: 84/345 - (24%)

  Fly    50 IKVYTPSKHN---DLCMMSITADINRFSMIPDKNTFFHVLK-----------LERHFDRMIATRK 100
            :.|.|...|.   :..:.|:|:.:...|....:....||||           :|..:..|....
 Worm   139 LHVATHGGHTKVVEALVASVTSALASLSTEESEGLNPHVLKDEDGNTALYYAIEGRYLEMATCL- 202

  Fly   101 QPDVTGDMAIQILSGHNTTFMSKYRRYKTRSAAKELKRRNQRFKALDVRRHTQLPDSGNDDSCIY 165
               |..|.....| |:|....|.|......:..::|.:...:....:|.|..:   ..|.||.:.
 Worm   203 ---VNADKDAPFL-GNNKGISSLYEAVDAGNKFEDLVKAILKTTDDNVDREVR---KFNLDSKLQ 260

  Fly   166 TNRTSFDVPTISLEEDKLDIKDVVESMASDEIP--VEEKNKELEECELVLNKIRLNRTLQKIEEL 228
            .|:   .:..::|:...:.:.||:    .||.|  ::|::::...|......|...:.|..|...
 Worm   261 GNK---HLAHVALKAKSIGVLDVI----LDEYPSLMDEQDEDGRTCLSYGASIGYYKGLCNILNR 318

  Fly   229 EKKNVSVVCELTKPETVVAAPVQVENVIISLPVKEDDSLAISAAKAN--------LIQKKHQSK- 284
            ..|.| .||:                        :|.|..|.:|..|        .|::...||
 Worm   319 STKGV-YVCD------------------------QDGSFPIHSAAKNEHYEIIKEFIKRCPASKY 358

  Fly   285 --SSTEKSMMSVTKKHEAKFKVAKSVTVKKDKTEKSENLKSDVPEKT-----------NEVTIAA 336
              :...::::.|..|:||..   .:..:..||..|...:..||...|           :.:|..|
 Worm   359 LLNRLGQNILHVAAKNEASL---TAYMLMHDKDTKHLGVGQDVDGNTPLHLAVMNWDFDSITCLA 420

  Fly   337 SLLEDVMEQLNLDDKKNTKA 356
            |...::   |.|.:|...:|
 Worm   421 SRNHEI---LKLRNKSGLRA 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	39/200 (20%)
sek-6	NP_509683.1	Protein Kinases, catalytic domain	57..343	CDD:473864	46/243 (19%)