Protein Alignment hep and mkk-4

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_509682.1
• Gene: mkk-4 / 185682
• WormBaseID: WBGene00003368
• Length: 363
• Species: Caenorhabditis elegans
• Alignment Length: 341
• Identity: 135/341 - (39%)
• Similarity: 189/341 - (55%)
• Gaps: 42/341 - (12%)

  Fly   166 VSETDMKLKIIME--------QTGKLNINGRQ------------------YPTDIN-------DL 197
            |.|.|..|:..|.        :...|::||.:                  ||.|.:       :|
 Worm     2 VQEDDENLRNSMSLRPTSLSTRPTSLSVNGNEKTLPEESVLRSLSTGTLKYPDDEHLYTFSSANL 66

  Fly   198 KHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMR--RTGNAEENKRILMDLDVVLKSHDCKYIVKCL 260
            :.||.:|||..|.|.||.|..:..:||||::|  ..|:.|: .|:|.:.|.::||.....|||..
 Worm    67 QDLGAIGNGNFGTVYKMRHKETGKLIAVKRIRCNNIGHREQ-IRLLREHDTIVKSEKGPNIVKFY 130

  Fly   261 GCFVRDPDVWICMELMSMCFDKLLK----LSKKPVPEQILGKVTVATVNALSYLKDKHGVIHRDV 321
            |....:.|.|||||||.:..|.|.|    :....:.|.::|.:||.||:||.|||.:..:|||||
 Worm   131 GAIFSEGDCWICMELMDISMDLLYKRVYMVKNSRLNENVVGHITVCTVDALDYLKKELKIIHRDV 195

  Fly   322 KPSNILIDERGNIKLCDFGISGRLVDSKANTRSAGCAAYMAPERIDPKKPKYDIRADVWSLGITL 386
            ||||||:|..|.:|||||||.|:|.:|.|.|..|||..|:||||| ....|||:|:|||||||||
 Worm   196 KPSNILVDGTGAVKLCDFGICGQLEESFAKTHDAGCQPYLAPERI-TSSDKYDVRSDVWSLGITL 259

  Fly   387 VELATARSPYEGCNTDFEVLTKVLDSEPPCL-PYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPEL 450
            .|:||.:.||:..|:.|:.:..|:..:||.| |..:.:::|.....|:..||||:.:.||||..|
 Worm   260 YEIATGKFPYQEWNSLFDQIATVVSGDPPILHPDSDDFHYSLPLVKFINTCLTKDRRHRPKYDTL 324

  Fly   451 LAQPFIRIYESAKVDV 466
            .:..|.|||..|..::
 Worm   325 KSFDFYRIYAVAGPEI 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	130/318 (41%)
mkk-4	NP_509682.1	PKc_MKK4	59..347	CDD:270790	124/284 (44%)