Protein Alignment hep and jkk-1

DIOPT Version :9

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_001370369.1
• Gene: jkk-1 / 180810
• WormBaseID: WBGene00002177
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 342
• Identity: 129/342 - (37%)
• Similarity: 196/342 - (57%)
• Gaps: 28/342 - (8%)

  Fly   157 PLPTPPHPPVSETD---MKLKII--MEQTGKLNINGRQYPTDINDLKHLGDLGNGTSGNVVKMMH 216
            ||...|.|...:|:   ::.:.:  .:::|.|.|:|.:...|.|::..:..||:|:.| ||:...
 Worm    77 PLSMKPSPSRRDTEKDALEYEFLEGYKKSGTLEIDGEKQVVDPNEIHIISLLGSGSCG-VVESAT 140

  Fly   217 LSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDCKYIVKCLGCFVRDPDVWICMELMSMCFD 281
            :.|. ::|||.|.:..|.|..||||.|:. ::...:..:||...|.|:.|..|.|||::||.|.:
 Worm   141 VRSK-LMAVKTMYKNDNKENLKRILRDVR-IMSMCNSPFIVTSYGYFMFDSSVKICMQIMSACCE 203

  Fly   282 KLLKL---SKKP-VPEQILGKVTVATVNALSYLKDKHGVIHRDVKPSNILIDERGNIKLCDFGIS 342
            |||:.   ||.. .||.:.|.:..:.::||.|||:||.:||||:||||||.|:.||:||||||||
 Worm   204 KLLRRIYHSKLDFFPEFVAGHIVYSAISALDYLKEKHSIIHRDIKPSNILFDDSGNVKLCDFGIS 268

  Fly   343 GRLVDSKANTRSAGCAAYMAPERID-PKKPKYDIRADVWSLGITLVELATARSPYEGCNTDFEVL 406
            |.:.||.|:::||||..||||||:. ....|||:|:||||||||:.:|.|...|:...:.:|..|
 Worm   269 GFMTDSMAHSKSAGCPPYMAPERLTIETNSKYDVRSDVWSLGITVYQLVTGLYPFPLNDMEFTTL 333

  Fly   407 TKV--LDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQDRPKYPELLAQPFIRIYESAK------ 463
            |.:  |:...|.|......:||..|.:|:..||.|:.::||:|.:|:...|...|:.|.
 Worm   334 TIIANLNLPSPSLREETKRSFSPLFIEFLDLCLRKDVRERPEYRQLMKHDFYLDYDPASGSAYKF 398

  Fly   464 -------VDVPNWFQSI 473
                   ..|.:||..:
 Worm   399 KAINGKCNQVADWFVDV 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	124/313 (40%)
jkk-1	NP_001370369.1	PKc_MKK7	106..418	CDD:270791	124/313 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0983
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1923
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D470057at33208
OrthoFinder	1	1.000	-	-		FOG0005845
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4836
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.730