Protein Alignment hep and cst-2

DIOPT Version :10

• Sequence 1: NP_001368982.1
• Gene: hep / 32256
• FlyBaseID: FBgn0010303
• Length: 1294
• Species: Drosophila melanogaster
• Sequence 2: NP_001370484.1
• Gene: cst-2 / 180707
• WormBaseID: WBGene00016038
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 428
• Identity: 120/428 - (28%)
• Similarity: 192/428 - (44%)
• Gaps: 63/428 - (14%)

  Fly   191 PTDINDLKHLGDLGNGTSGNVVKMMHLSSNTIIAVKQMRRTGNAEENKRILMDLDVVLKSHDC-- 253
            |.::.|:  :|.||.|:.|:|.|.:|..|..::|:|::....:.:|   |:.::.::   ..|
 Worm    31 PEEVFDI--VGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQE---IIKEISIM---QQCKS 87

  Fly   254 KYIVKCLGCFVRDPDVWICMELMSM-CFDKLLKLSKKPVPEQILGKVTVATVNALSYLKDKHGVI 317
            ||:||..|.:.:..|:||.||.... ....:::..:||:.||.:..|...|:..|.||.|.. .|
 Worm    88 KYVVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLK-KI 151

  Fly   318 HRDVKPSNILIDERGNIKLCDFGISGRLVDSKANTRSA-GCAAYMAPERIDPKKPKYDIRADVWS 381
            |||:|..|||::..|..||.|||::|:|.|:.|...:. |...:||||.|:  :..||.:||:||
 Worm   152 HRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIE--EIGYDTKADIWS 214

  Fly   382 LGITLVELATARSPYEGCN---TDFEVLTKVLDSEPPCLPYGEGYNFSQQFRDFVIKCLTKNHQD 443
            ||||.:|:|..|.||...:   ..|.:.||    .||.....|  .:|.:|.||:..||.|..::
 Worm   215 LGITAIEMAEGRPPYSDIHPMRAIFMIPTK----PPPTFKKPE--EWSSEFNDFIRSCLIKKPEE 273

  Fly   444 RPKYPELLAQPFIRIYESAKVDVPNWFQSIKDNRLRANGDPTLQR--ATATGSAIGSGAGSLAGS 506
            |.....|....||:                     .|.|...:|.  ..|...|| .|...:|.|
 Worm   274 RKTALRLCEHTFIK---------------------NAPGCDIMQLMIQDAQEKAI-LGQAPMAAS 316

  Fly   507 GSGSAGGAVKYGRATTYAGQSPTNPQKTIKPTQIPSYQQQQSQFFMQSATQLPQTTTTTPTATTN 571
             ||:....:..|.:|...|...|..|.  |...:.:...:.....::...::|:          :
 Worm   317 -SGNDATLLSEGMSTMIDGGESTLVQH--KDNYVTAQSLRSQMESLRIGGEIPK----------S 368

  Fly   572 CFGGSGNGNG-RGNGSGGSGNGSGSSSSASPLSPPSAG 608
            .:..|.|||. |....|.:.:.|..|.: .|.:....|
 Worm   369 AYSSSKNGNSPRVQPPGHTASASDPSKN-QPFAQDGTG 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hep	NP_001368982.1	PKc_MKK7	181..476	CDD:270791	92/291 (32%)
cst-2	NP_001370484.1	STKc_MST1_2	31..286	CDD:132943	90/271 (33%)