Protein Alignment rsh and RALGAPA2

DIOPT Version :10

• Sequence 1: NP_001285176.1
• Gene: rsh / 32253
• FlyBaseID: FBgn0265597
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: XP_006723661.1
• Gene: RALGAPA2 / 57186
• HGNCID: 16207
• Length: 1970
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 66/273 - (24%)
• Similarity: 112/273 - (41%)
• Gaps: 39/273 - (14%)

  Fly   862 ELLKLDQVFIKSELKVGVIFVKEDQYTEEQILDNNENSPLFDEFLTLLGDRVRLRGFDKYKGGLD 926
            ||..||....:...|:.|.::.|.|..:..||.|...|..:::|:..||..|.|.....:.|||.
Human  1681 ELKNLDSRQCRETHKIAVFYIAEGQEDKCSILSNERGSQAYEDFVAGLGWEVDLSTHCGFMGGLQ 1745

  Fly   927 TVHDLTGLFSVYTNWRNIEIMFHVSTLLPYEKHDPQKLQRK-RHIGNDIVCVVFLEADNTRFSPA 990
            . :..||..:.|.....:|::|||||.:|.:..|  .|.:| ||:|||.|.:|:.| .:..:...
Human  1746 R-NGSTGQTAPYYATSTVEVIFHVSTRMPSDSDD--SLTKKLRHLGNDEVHIVWSE-HSRDYRRG 1806

  Fly   991 CIKSHFLHTFILVRVSARIKHKPTRYEVSVVTRDEVGAYKPYLWEQSVFEKGPMFREWLLTKIVN 1055
            .|.:.|....|::     ...|...:.:::..:.||..:.| |::.::. .|.:....:....:|
Human  1807 IIPTAFGDVSIII-----YPMKNHMFFIAITKKPEVPFFGP-LFDGAIV-SGKLLPSLVCATCIN 1864

  Fly  1056 GERA-SYSAPKFARMQERTRSQMLEDLVMNLSNHAE----------------------TGQIPKP 1097
            ..|| ....|.:....|. |:..||.::   .||.|                      ||.:...
Human  1865 ASRAVKCLIPLYQSFYEE-RALYLEAII---QNHREVMTFEDFAAQVFSPSPSYSLSGTGALASS 1925

  Fly  1098 YRRGSWRPIGEDE 1110
            .......|:.|:|
Human  1926 LSADLEEPLSEEE 1938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rsh	NP_001285176.1	PHA03309	<207..539	CDD:165564
		LIM	<583..623	CDD:259829
		Rap_GAP	893..1074	CDD:460463	46/182 (25%)
		BTB_POZ	1289..>1344	CDD:453885
		BTB	<1467..1526	CDD:197585
		BACK	1531..1603	CDD:475122
RALGAPA2	XP_006723661.1	RALGAPB_N	534..658	CDD:466561
		Rap_GAP	1712..1884	CDD:460463	46/183 (25%)