DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment rad and ralgapa2

DIOPT Version :9

Sequence 1:	NP_001285176.1	Gene:	rad / 32253	FlyBaseID:	FBgn0265597	Length:	1799	Species:	Drosophila melanogaster
Sequence 2:	XP_001920508.2	Gene:	ralgapa2 / 568210	ZFINID:	ZDB-GENE-131122-56	Length:	2015	Species:	Danio rerio

Alignment Length:	259	Identity:	69/259 - (26%)
Similarity:	120/259 - (46%)	Gaps:	34/259 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   862 ELLKLDQVFIKSELKVGVIFVKEDQYTEEQILDNNENSPLFDEFLTLLGDRVRLRGFDKYKGGLD 926
            ||..||....:...|:.|.::.|.|..:..||.|.:.|.::::|::.||..|.|.....:.|||.
Zfish  1724 ELKNLDSRQCRETHKIAVFYIGEGQEDKYSILSNTQGSQVYEDFVSGLGWEVNLATHCGFMGGLQ 1788

  Fly   927 TVHDLTGLFSVYTNWRNIEIMFHVSTLLPYEKHD--PQKLQRKRHIGNDIVCVVFLEADNTR-FS 988
            . :..||..:.|....|:|::|||||.:|.:..|  .:||   ||:|||.|.:|:  :::|| :.
Zfish  1789 R-NGSTGSTAPYYATSNVEVIFHVSTRMPSDSDDSITKKL---RHLGNDEVHIVW--SEHTRDYR 1847

  Fly   989 PACIKSHFLHTFILVRVSARIKHKPTRYEVSVVTRDEVGAYKPYLWEQSVFEKGPMFREWLLTKI 1053
            ...|.:.|....:::     ...|...:.|.::.:.:|..:.| |::.::. .|.:....:....
Zfish  1848 RGIIPTDFGDVLVII-----YPMKNHMFFVQIMKKPQVPFFGP-LFDGAIV-TGELLPSLVRATC 1905

  Fly  1054 VNGERASYS-APKFARMQERTRSQMLEDLVMNLSNHAE-------TGQI--PKPYRRGSWRPIG 1107
            :|..||..| .|.:....|. |:..||.::   .||.|       ..|:  |.|    |:.|.|
Zfish  1906 INASRAVKSRLPLYQSFYEE-RALYLEAII---QNHKENMTFEDFAAQVFSPSP----SYWPSG 1961

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rad	NP_001285176.1	LIM	<583..623	CDD:259829
		Rap_GAP	893..1074	CDD:280332	48/184 (26%)
		BTB	<1464..1523	CDD:295341
		BTB	<1467..1526	CDD:197585
		BACK	1544..1646	CDD:197943
ralgapa2	XP_001920508.2	Rap_GAP	1755..1927	CDD:280332	48/185 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910