Protein Alignment rad and Rap1gap2

DIOPT Version :9

• Sequence 1: NP_001285176.1
• Gene: rad / 32253
• FlyBaseID: FBgn0265597
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: XP_006533687.1
• Gene: Rap1gap2 / 380711
• MGIID: 3028623
• Length: 790
• Species: Mus musculus
• Alignment Length: 584
• Identity: 185/584 - (31%)
• Similarity: 281/584 - (48%)
• Gaps: 119/584 - (20%)

  Fly   629 MECSDFMQQLRSFKPQSLGCAVAR---RKSSTTLIFPLPPQACSDEFCEE---YPHNLMPT-PGY 686
            |:.::|.:.|.  |.|.:.....|   :|:....|    |....||..|:   ||..::|. .||
Mouse   113 MKSAEFFEMLE--KMQGIKLEEQRPGPQKNKDDYI----PYPSIDEVVEKGGPYPLIILPQFGGY 171

  Fly   687 WIECSRQKITMPTPHTIWDESDSEHEDIRAGSASDAYLERECSDLYEDDEDSEATPSPRKKTTIE 751
            ||| ..:.:..||               ..||:           :||::|:...:|:     |..
Mouse   172 WIE-DPENVGTPT---------------SLGSS-----------VYEEEEEDSLSPN-----TFG 204

  Fly   752 EQWDQQGAFELISVEQETYEKYFYGTEHWNYFTSDEDLGPVILSIKQETLNGRDQFRILVRAGSY 816
            .:.:.:|       |...|.::|.|.:|.|::.:...||.:|||||.|...|.:..||::|:...
Mouse   205 YKLECRG-------EARAYRRHFLGKDHLNFYCTGSSLGNLILSIKCEEAEGMEYLRIILRSKLK 262

  Fly   817 TVHGLIPASCVFADRYNREEVVRSLGKE-------VNLNPPLTLGQLPDTPEELLKLDQVFIKSE 874
            |||..||.:.:     ::...|..:.|.       :..||.|    .|...:.::..|:..:.:.
Mouse   263 TVHERIPLAGL-----SKLPSVPQIAKAFCDDAVGLKFNPVL----YPKASQMIVSYDEHDVNNT 318

  Fly   875 LKVGVIFVKEDQYTEEQILDNNENSPLFDEFLTLLGDRVRLRGFDKYKGGLDTVHDLTGLFSVYT 939
            .|.|||:.|..|..||::..|||.||.|.|||.||||.:.|:.|..::||||..|..||:.||||
Mouse   319 FKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVESVYT 383

  Fly   940 NWRNIEIMFHVSTLLPYEKHDPQKLQRKRHIGNDIVCVVFLEADNTRFSPACIKSHFLHTFILVR 1004
            .:|:.||||||||.||:...|.|:||||||||||||.::|.| :||.|.|..|.|:|||.:|:|:
Mouse   384 TFRDREIMFHVSTKLPFTDGDTQQLQRKRHIGNDIVAIIFQE-ENTPFVPDMIASNFLHAYIVVQ 447

  Fly  1005 VSARIKHKPTRYEVSVVTRDEVGAYKPYLWEQSVFEKGPMFREWLLTKIVNGERASYSAPKFARM 1069
            ........|: |:|||..|::|.|:.|.|....||:||..|||:||||:.|.|.|...:.|||::
Mouse   448 ADNPGTETPS-YKVSVTAREDVPAFGPPLPSPPVFQKGAEFREFLLTKLTNAENACCKSDKFAKL 511

  Fly  1070 QERTRSQMLEDLVMNLSNHAET--GQIPKPYRRGSWRPIGEDEYIKMLHARVLDNNTHH---EQQ 1129
            ::|||:.:|::|...|..|.:.  |..|:           ||::         :|..|.   |..
Mouse   512 EDRTRAALLDNLHDELHTHTQVMLGMGPE-----------EDKF---------ENGGHGGFLESF 556

  Fly  1130 QQLLLQQQHMQHTQ-------HMQHLPSHNICCYCNNNATELHTAGAIHNNNDNNNTTTTTTFT 1186
            ::.:..:.|...|.       |..:||..             .:.|.:||:.:    .|.|||:
Mouse   557 KRAIRVRSHSMETMVGSQRKLHGGNLPGS-------------LSGGIVHNSME----VTKTTFS 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rad	NP_001285176.1	LIM	<583..623	CDD:259829
		Rap_GAP	893..1074	CDD:280332	92/180 (51%)
		BTB	<1464..1523	CDD:295341
		BTB	<1467..1526	CDD:197585
		BACK	1544..1646	CDD:197943
Rap1gap2	XP_006533687.1	Rap_GAP	337..516	CDD:366939	92/180 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D163377at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920