Protein Alignment rsh and LOC1273968

DIOPT Version :10

• Sequence 1: NP_001285176.1
• Gene: rsh / 32253
• FlyBaseID: FBgn0265597
• Length: 1799
• Species: Drosophila melanogaster
• Sequence 2: XP_061497090.1
• Gene: LOC1273968 / 1273968
• VectorBaseID: AGAMI1_006025
• Length: 2252
• Species: Anopheles gambiae
• Alignment Length: 1463
• Identity: 276/1463 - (18%)
• Similarity: 425/1463 - (29%)
• Gaps: 545/1463 - (37%)

  Fly    39 SHQVGLVWQGGNGWDDLVREQLEESTIRQRLGGRRDSAAQITTPPSTS--------------PPP 89
            :|..|.....|:|.:   |..|:|.  |...||...|....||..:||              ..|
Mosquito   732 AHMGGSANGAGSGQN---RTGLDED--RMINGGGAGSMTNATTSTATSVAGVMRLQSTRSIPGTP 791

  Fly    90 GLQR-----------------RRRSSLAQLTDILREWSGGTKQQQQHHSQQQQQQLQQASRSKAQ 137
            .|.|                 |||..:|.|...:     |...::.|.:.:|...:...|.|:..
Mosquito   792 SLNRSYSEGSLMSAPFRKSRARRRLRIAGLGLTM-----GGNSREHHTAAEQHHHMADHSFSRLL 851

  Fly   138 LNRRETLADLARSLPWRT-STTTDASTGAG-----------------------GSGGGGCTTYMA 178
            .|....|:..:.:|...: |..|:...|..                       |||.|
Mosquito   852 SNTSTFLSISSENLEMASFSECTEVPLGGDSQVGSVVGGVVRRAVSLDSVRPPGSGSG------- 909

  Fly   179 PRKRRESSADSGIRSMR---------SRRDSNTAEFVRHWNRRESGAVEEQPSVSVPVVVECSKS 234
              |:|....|...|..|         ||..|.||.     :..|||::::.|.....|:...|.|
Mosquito   910 --KKRHPDEDGYHRHSRVGASCEAGGSRSPSPTAS-----SGIESGSIKDSPMQIADVLTADSSS 967

  Fly   235 ASRR-------GSGESYLSSSRRDSNVAG--------------------------RVTTPPPPGK 266
            ...:       ||..|..::|.|.|.:||                          ::..|....:
Mosquito   968 IDTQDDPQSFGGSSSSMATTSDRRSILAGGTAKGWLPDVAAVMWRRMLGALGDVNKILNPKLHAQ 1032

  Fly   267 -YQ----MTK---------------KRDSLAAPEFPNFRQEQRP--------------------- 290
             ||    ||:               ...|..:..|||......|
Mosquito  1033 VYQYLVSMTESLIKIRMNQGISLDGSGHSSTSSAFPNGTNLVPPVALVAPWCYGALALDAQYAQG 1097

  Fly   291 ----------STSSAGSCSDHSMPLISTHSSTHHLAHQQVDSACQA------------------L 327
                      ...|..|..::.:||.      :|..||.:....:|                  |
Mosquito  1098 KLYAMQLLCTIVQSGASLGNNQLPLF------YHALHQALTGEDRAMAYTALRYLGGPRFLSLLL 1156

  Fly   328 PPPTIITSSVTPPAT-----SPTAPKGRRDSQTQCGRVNRRDSKAGVSPERAPRLQ--RLQRQAT 385
            |..|::...:...||     |.|.|                         .|||.|  .|.....
Mosquito  1157 PGHTLLLLDLVHAATVVLTSSETGP-------------------------NAPRAQVAGLLGSLL 1196

  Fly   386 AFDEGCLPGGSRRGSQPALS----PDPPDD-------CERR--TSR--------------RDSLS 423
            .|....|||...:.|:|.:.    ||..:.       |.||  |::              ::..:
Mosquito  1197 CFPRTSLPGPVLQPSEPHIDLMECPDLQEHVLNVVLRCARREPTAKARCIAIASLGQWILQNLTN 1261

  Fly   424 PDSASRGG--------------------RRDSRTHLSPDRSHE------RDGSPRRHTLRR---- 458
            |.....||                    ||||.||....|..|      :....:.||:.|
Mosquito  1262 PTGQHNGGDGEPAFKQKVPQHSSEASSARRDSVTHTVNPRIREAFQVILQALQFKHHTIARLASE 1326

  Fly   459 -------QSSSAARSPRSPD--SNSCCSSRD----PSPCSRPQTQTT--------------VEQN 496
                   |.:...:..|.|.  .::.|.|.|    |.|....:|..|              |...
Mosquito  1327 TLKLCAEQGARIEQIERLPQLIIDTVCLSLDIHNVPHPKESDKTVLTSLLLTLGELCMSFSVRTL 1391

  Fly   497 QRPAIRRQSTTEEIL---------IARGFR-----------------------RQS--------- 520
            |:|  :...:||.::         ||.|.:                       |:|
Mosquito  1392 QQP--KHHDSTEPLILIVFRILYKIATGLQNGERIKLFTTDEDFDSTIVVDDVRESGSGGIGEAG 1454

  Fly   521 ---TTEEMIRCRN-------------------------FRRQSS---QSDDVCRYRGRRDSSAQI 554
               |.|.:..|::                         ..|.||   :.||:....|   ::|.:
Mosquito  1455 GYQTAETIASCQSAIRLCAKTVAMHLITNLGHFPMGIGATRLSSLVDEQDDLMSATG---AAAPV 1516

  Fly   555 IDGTIGT----------------------------------MTVETTSTFFDSSTQTEPSP---- 581
            ..|..|.                                  ::.|..::|.:......|..
Mosquito  1517 HPGVSGAAPSVAMLQRENSIAGARVDAMEHVLASPNLQLLMLSPELVASFIELPALKLPGGGATA 1581

  Fly   582 ------------LYDNNH---------YHEECLRCNSCGLNLTGPNQKRARRFKNQILCDLHFAD 625
                        |.|.|.         |.|..|   |.|.|.|..|    ..|::......|:|.
Mosquito  1582 GLLTANRQVRLLLRDLNGKACWDASILYQEPAL---SAGSNDTDRN----ATFQSAAPVSRHYAF 1639

  Fly   626 VALMECSDFMQQLRSFKPQSLGCAVARR-KSSTTLIFPLPPQACSDEFCEEYPHNLMPTPGYWIE 689
            ..:...|.   ||     ...|...||. .|.:..|.||...|..........|.|...|.:.:.
Mosquito  1640 ATVPTGSG---QL-----AGAGSVTARHFASGSASIDPLMSTAIGLPMSHGPRHTLRHRPVHQLP 1696

  Fly   690 CSRQKITMPTPHTIWDESDSEHEDIRAGSASDAYLERECSDLYEDDEDSEATPSPRKKTTIEEQW 754
            .::..    .|..  |:.|...:.|       .|...||.|..|...:: |.|||.....
Mosquito  1697 VAKDL----APDL--DQLDDLLQYI-------GYTSPECLDSSEVPLNT-AGPSPLGAAL----- 1742

  Fly   755 DQQGAFELISVEQETYEKYFYGTEHWNYFTSDEDLGPVILSIKQETLNGRDQFRILVRAGSYTVH 819
              :|....|.:.|.|.|......:  |..|:.:.      .:.:...:|...:..||.:..|..:
Mosquito  1743 --EGQTISIILNQRTIEAEAVARQ--NAGTTGQP------GVDRSLPSGTSSYPTLVSSSGYGSY 1797

  Fly   820 ------------GLIPASCVFADRYNREEVVRSLGKEVNLNPPLTLGQ----------------- 855
                        |.|..:   |:....::..:.|.:......|..||:
Mosquito  1798 SPGQSYSDDSGTGTIARA---ANTMQTQQQQQQLDRSDATTKPFQLGRILFNQLGLAGWERRKRT 1859

  Fly   856 --LPDTPE---ELLKLDQVFIKSELKVGVIFVKEDQYTEEQILDNNENSPLFDEFLTLLGDRVRL 915
              |..|.:   ||..||....:...|:.||:|...|..:..||.|...|..::.|::.||..|.|
Mosquito  1860 HLLQRTDKLLRELRNLDNQKCRETHKMAVIYVANGQEDKGSILRNACGSSTYEMFVSALGWEVEL 1924

  Fly   916 RGFDKYKGGLDTVHDLTGLFSVYTNWRNIEIMFHVSTLLPYEKHDPQK-LQRKRHIGNDIVCVVF 979
            ...:.:.|||.  ....|..:.|.....:|:::||||.:|.:  .|:. |.:.||:|||.|.:|:
Mosquito  1925 ESHNGFLGGLP--RQGCGQTAPYYATPFLEVIYHVSTRMPSD--TPEAILNKTRHLGNDEVHIVW 1985

  Fly   980 LEADNTRFSPACIKSHFLHTFILVRVSARIKHKPTRYEVSVVTRDEVGAYKPYLWEQSVFEKGPM 1044
            .| .|..:....:.:.|....|::     ...|...:.|:|..:.||..:.|...|..|  .|..
Mosquito  1986 SE-HNRDYRRDILPTEFCDVLIVI-----YPLKSGLFRVTVNKKPEVPWFGPLSDEMVV--GGAC 2042

  Fly  1045 FREWLLTKIVNGERASYSA-PKFAR-MQERTRS 1075
            ....:....:|..||..|: |.:.: .:||.||
Mosquito  2043 LASLVRASAINASRAKRSSLPLYQQYYEERNRS 2075

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rsh	NP_001285176.1	PHA03309	<207..539	CDD:165564	98/596 (16%)
		LIM	<583..623	CDD:259829	11/48 (23%)
		Rap_GAP	893..1074	CDD:460463	48/183 (26%)
		BTB_POZ	1289..>1344	CDD:453885
		BTB	<1467..1526	CDD:197585
		BACK	1531..1603	CDD:475122
LOC1273968	XP_061497090.1	None