DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12715 and CG3655

DIOPT Version :9

Sequence 1:	NP_001285181.1	Gene:	CG12715 / 32252	FlyBaseID:	FBgn0030443	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_001259118.1	Gene:	CG3655 / 31056	FlyBaseID:	FBgn0040397	Length:	596	Species:	Drosophila melanogaster

Alignment Length:	457	Identity:	147/457 - (32%)
Similarity:	224/457 - (49%)	Gaps:	59/457 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 PNLEELLRSKEDVDWVRLRADQCAPYPRYEDIEFPNPYFQLTRHENLSYYLYGAYYD-RRPRI-- 138
            |:|.....|| :.::::.::..||.||...::||.|.|:|..|..|.::.|:||||| ||..:
  Fly    92 PSLPIAYWSK-NKNFLQQKSSTCAKYPSIFELEFNNIYWQTLRTSNGTFQLFGAYYDIRRTSLLG 155

  Fly   139 PEMVVLGMATYNGSYPATYLQVWYDGDNQPEKLPVYQSKLGWYKEWG-LPEGVVFPTLLTFQMKS 202
            |.:.:|||.........||.|.|:||..:|..:..::.|..||.:|| ..:|:..|.|:..|:..
  Fly   156 PTVRILGMIDRIEPKVKTYCQFWFDGQKEPFIVKTFEYKYIWYNKWGNYKQGIYQPYLIACQIPK 220

  Fly   203 Q---RVPQLVSLVFDPCAVPTNAFKVVPPPPEEPPNAQRPKRIGVCVKYLRFPDVDMTDRFVEWL 264
            .   .||..||:|...|...||..:|:   ...||:.|: |...||||.|.|...|::.|.:||:
  Fly   221 PFHGVVPSSVSMVEKECDTATNNLRVI---YNRPPDDQK-KGFAVCVKGLDFLYDDLSVRLIEWI 281

  Fly   265 ELMRLLGATKVTAFDIGLLMPNTRRTLAHYTGAG----------------DGFLDLRKFRFPNET 313
            |::.:|||.|:..::: .:.||..:.|.||...|                .||..|...:..|..
  Fly   282 EMLNILGADKIYFYNL-QVHPNITKVLNHYEQEGKVQVIPLTLPGGQPNVPGFQHLYLTKKTNHK 345

  Fly   314 ADHETFRAMIIEVLLYNDCLYRNLYDFDFVAVVDVDEVIMPLGEHRTWQDLLTHLQVQD--VNST 376
            ..:        ||:.||||||:|||.:|::|::|:||||||.|....|.:|:..::.:.  :...
  Fly   346 RQN--------EVIPYNDCLYKNLYLYDYIALLDIDEVIMPKGGAVLWSELMDKVRPESRKIKPD 402

  Fly   377 TRSSYCFRNVYFSKQLPVDE---------SIPEQFFMLRHVIRVAEHLDPYSAIKCLHDTSYVTL 432
            ...||.||||||     :|:         .||:...||:||.|...:..|...:||.||...|..
  Fly   403 GFHSYNFRNVYF-----LDDQQHEHGWHKDIPKYMHMLQHVHRAKNYTKPNQYVKCFHDPERVLT 462

  Fly   433 LHNHFPFQWM-NASDPYHVGIDLGQMQHYR--YTENLKSLVE---PPPVRDDNIRRFQHQLIHNS 491
            ||||||...: .....|.|.....|:||||  ..:.||...|   ...|.|..|.:::.:||..:
  Fly   463 LHNHFPLSCLGGVCKSYPVDTKDAQLQHYRADCVKTLKKSCEEYREHSVEDKTIWKYKDELIRRT 527

  Fly   492 LE 493
            ::
  Fly   528 IK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12715	NP_001285181.1	Glyco_transf_92	240..496	CDD:279961	92/287 (32%)
CG3655	NP_001259118.1	Glyco_transf_92	257..527	CDD:279961	92/283 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4735
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I4894
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561250at33208
OrthoFinder	1	1.000	-	-		FOG0012699
OrthoInspector	1	1.000	-	-		otm14086
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900