DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12715 and C08B6.3

DIOPT Version :9

Sequence 1:	NP_001285181.1	Gene:	CG12715 / 32252	FlyBaseID:	FBgn0030443	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_505599.2	Gene:	C08B6.3 / 182389	WormBaseID:	WBGene00007424	Length:	439	Species:	Caenorhabditis elegans

Alignment Length:	510	Identity:	99/510 - (19%)
Similarity:	174/510 - (34%)	Gaps:	144/510 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LFVVYLLYQSLGSLQVLNNPQGTISQPASRPKKVAVVHHGAHPGIDTEGKESAGSQQEPNLEELL 83
            ||.:.:|| |..|     .|..::...:                    |.|...:..|.|.:||.
Worm    15 LFTIVILY-SFNS-----TPTNSLQSKS--------------------GSEVISTTVELNPKELP 53

  Fly    84 RSKEDVDWVRLRADQCAPYPR--YEDIEFPNPYFQLTRHENLSYYLYGAYYDRRPRIPEMVVLGM 146
            ..|.|      |.|:...|.|  .|:|:                      .|:.|:|.|:.:|..
Worm    54 TYKID------RMDRFEWYTRKWKEEIK----------------------KDQPPKIEEVSMLRA 90

  Fly   147 ATYNGSY------PATY---LQVWYDGDNQPEKLPVYQSKLGWYKEWGLPEGVVFPTLLTFQMKS 202
            ..::..|      |..|   |...|..::..|.||.:||       :..||.||       ..:.
Worm    91 YEFDVEYSISITTPGKYKAILYCRYFDESGVELLPSFQS-------YNFPEFVV-------NCQK 141

  Fly   203 QRVPQLVSLVFDPCAVPTNAFKVVPPPPEEPPNAQR--PKRIGVCVKYLRFPDVDMTDRFVEWLE 265
            ::..:.||       |.|.|......|.|.....||  .:.:..|:.       .:..:..:||.
Worm   142 RKGTKRVS-------VSTQATNNYTYPIELHDRTQREYKRELSFCMS-------PIYGKEAKWLL 192

  Fly   266 LMRLLGATKVTA-----FDIGLLMPNTRRTLAHYTGAGDGFLDLRKFRFPNETADHETFRAMIIE 325
            |..::...|:..     |.|..:...:...|..|...|:     .:..:..|..|.|...   .:
Worm   193 LAEIIEHYKLQGMTHFYFYIFHIDEYSSAMLNDYVRTGE-----VEVTYLQERNDRELLH---WQ 249

  Fly   326 VLLYNDCLYRNLYDFDFVAVVDVDEVIMPLGEHRTWQDLLTHLQVQDVNSTTRSSYCFRNVYFSK 390
            ::.:.||..|:.::..:....|:||.::......|..|.|     ::||....:...:|..:..|
Worm   250 MVAFRDCTLRSRFESKWSLFSDIDERLLMTKYPGTILDYL-----KEVNDPKIAGVQYRQQWIMK 309

  Fly   391 QLPVDESIPEQFFMLRHVIRVAEHL---------DPYSAIKCLHDTSYVTLLHNH-----FPFQW 441
                .|.:|:::...:.:...:..|         .|...:||:.....|..:..|     ||..:
Worm   310 ----TEFMPDKYEGDKQIDEWSPTLRWHNSSVFGPPGHTVKCIIMPEKVFAMWTHRPTMIFPGFY 370

  Fly   442 MNASDPYHVGIDLGQMQHYRYTEN-------LKSLVEPPPV-RDDNIRRFQHQLI 488
            ::...|     :.|.::|||..:.       ||.:|...|: |.|...::|..||
Worm   371 VHELTP-----EEGIIRHYRDLQMWNWGKTWLKEIVAMGPMSRTDYPAKYQKPLI 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12715	NP_001285181.1	Glyco_transf_92	240..496	CDD:279961	50/276 (18%)
C08B6.3	NP_505599.2	Glyco_transf_92	174..419	CDD:366762	48/273 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D561250at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920